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. 2021 Jun 30;53:56. doi: 10.1186/s12711-021-00649-8

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Detection of tissues and cell types related to wool traits and live weight in sheep. a Functional enrichment analysis of tissue-specific genes (the top 10% of genes based on t-statistics) for 13 organ systems (central nervous system (CNS), cardiovascular system (Cardio), skin, muscle, liver, lung, kidney, gastrointestinal (GI) tract, endocrine (Endoc), immune system, male reproductive system (Male_R), female reproductive system (Fem_R), and embryonic system). b–d Relationships between the six economic traits and the 13 organ systems, GI tract tissues and immune tissues, respectively. The colour corresponds to the enrichment degree (i.e., − log₁₀FDR), which was computed by sum-based GWAS signal enrichment analysis based on the top 10% tissue-specific genes and a 20-kb extension. *corrected-P (FDR) < 0.05