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. 2021 Jun 30;12:48. doi: 10.1186/s13229-021-00456-4

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Region-of-interest analysis of WM areas involved in adults with autism. Left panel: WM areas obtained using the John Hopkins University’s ICBM-DTI-81 WM tractography and label atlases (only left side tracts are shown). Right panel: The mean of each measure in autism and TD groups (represented as the percentage difference from TD). Significant areas (Bonferroni-corrected P < 0.0022) are displayed in color, whereas nonsignificant tracts are shown in gray. ALIC, anterior limb of internal capsule; ATR, anterior thalamic radiation; CC, corpus callosum; CCG, cingulum cingulate gyrus; CST, corticospinal tract; FA, fractional anisotropy; IFOF, inferior fronto-occipital fasciculus; ILF, inferior longitudinal fasciculus; ISOVF, isotropic volume fraction; MD, mean diffusivity; NDI, neurite density index; RD, radial diffusivity; SLF, superior longitudinal fasciculus; UF, uncinate fasciculus; TD, typically developing