TABLE 3.
Abnormal Cognitive Function of MCI and AD Patients Is Positively Correlated With the Vulnerability of Central Regions
| Group | Correlation | Rank | ROI label | Cortex | R coeff | PFDR‐value |
|---|---|---|---|---|---|---|
| MCI | MPC‐MMSE | 1 | PCUN.L | Parietal | 0.417 | PFDR < 0.05 |
| 2 | SPG.L | Parietal | 0.296 | PFDR < 0.05 | ||
| 3 | HES.R | Temporal | 0.284 | PFDR < 0.05 | ||
| 4 | IPL.R | Parietal | 0.258 | PFDR < 0.05 | ||
| 5 | MFG.L | Frontal | 0.257 | PFDR < 0.05 | ||
| 6 | PreCG.L | Frontal | 0.232 | PFDR < 0.05 | ||
| AD | MPC‐MMSE | 1 | HES.R | Temporal | 0.782 | PFDR < 0.05 |
| 2 | SFGdor.R | Frontal | 0.713 | PFDR < 0.05 | ||
| 3 | PreCG.L | Frontal | 0.604 | PFDR < 0.05 | ||
| 4 | PCG.L | Limbic | 0.544 | PFDR < 0.05 | ||
| 5 | HIP.L | Limbic | 0.507 | PFDR < 0.05 | ||
| 6 | HES.L | Temporal | 0.474 | PFDR < 0.05 | ||
| 7 | PCUN.R | Parietal | 0.450 | PFDR < 0.05 | ||
| 8 | ORBmid.R | Frontal | 0.405 | PFDR < 0.05 | ||
| 9 | SFGmed.L | Frontal | 0.391 | PFDR < 0.05 |
The entries are sorted according to the obtained P values. The brain areas written in bold in the table belong to the hub regions that were significantly damaged in the corresponding subjects.