Figure 3.

(a) Comparison of receiver operating characteristic curves of Fusobacterium nucleatum (Fn), Lachnoclostridium sp. (m3), Clostridium hathewayi (Ch), Bacteroides clarus (Bc), and their combination (4Bac) in distinguishing colorectal cancer (CRC) and adenoma patients from non‐neoplastic controls in asymptomatic subjects. (b) Diagnostic performances of fecal immunochemical test (FIT), 4Bac and their combination for CRC, advanced adenoma (AA), and non‐advanced adenoma (NAA) in asymptomatic subjects. Significant P values are shown for comparison with FIT. Comparing “4Bac + FIT” with 4Bac, P values are not significant and not shown. 4Bac shows no difference in detecting AA and A in asymptomatic subjects (ns, not significant). ^#Specificity is the true negative rate in non‐neoplastic controls. AUC, area under ROC.