TABLE 1.
Demographics and laboratory parameters during follow‐up
| DLI readmission (n = 23) | DLI no readmission (n = 27) | P value* | No DLI (n = 133 a ) | P value** | |
|---|---|---|---|---|---|
| Age at implant, years | 59.0 (14.0) | 56.5 (14.3) | .77 | 58.0 (14.8) | .75 |
| Gender, male | 22 (81.5) | 21 (91.3) | .43 | 156 (85.0) | .77 |
| Weight, kg | 83.0 (22.3) | 81.3 (16.0) | .68 | 82.8 (23.8) | .29 |
| BMI, kg/m2 | 28.3 (7.0) | 26.1 (6.5) | .33 | 26.4 (6.6) | .12 |
| Smoking history, n (%) | 15 (65.2) | 10 (37.0) | .045 | 39 (29.3) | .001 |
| Diabetes, n (%) | 10 (47.8) | 8 (29.6) | .22 | 42 (31.6) | .15 |
| Device, n (%) | |||||
| HVAD | 16 (69.6) | 16 (59.3) | .76 | 79 (59.4) | .04 |
| HeartMate II | 2 (8.7) | 3 (11.1) | 38 (28.6) | ||
| HeartMate 3 | 5 (21.7) | 8 (29.6) | 16 (12.0) | ||
| Strategy, n (%) | |||||
| Destination therapy | 7 (29.6) | (27.2) | .36 | 38 (28.9) | .20 |
| Bridge to transplant | 4 (18.5) | 10 (36.4) | 48 (36.7) | ||
| Bridge to candidacy | 12 (51.9) | 10 (36.4) | 46 (33.6) | ||
| Bridge to recovery | 0 (0.0)% | 0 (0.0) | 1 (0.8) | ||
| INTERMACS level, n (%) | |||||
| 1 | 2 (8.0) | 3 (11.2) | .39 | 39 (29.6)% | .07 |
| 2 | 3 (12.0) | 4 (14.8) | 21 (16.0)% | ||
| 3 | 9 (40.0) | 10 (37.0) | 35 (25.6)% | ||
| 4‐7 | 9 (40.0) | 10 (37.0) | 38 (28.8)% | ||
| Albumin, g/L | 37.0 (7.4) | 42.9 (4.2) | <.001 | 42.1 (5.3) | <.001 |
| CRP, mg/dL | 2.93 (18.78) | 0.79 (2.20) | <.001 | 0.62 (1.10) | <.001 |
| Leukocytes, g/L | 10.41 (7.83) | 8.17 (4.31) | .026 | 7.39 (2.88) | <.001 |
| INR | 2.55 (1.12) | 2.60 (0.85) | .557 | 2.70 (0.70) | .549 |
| aPTT, s | 50.2 (21.1) | 46.0 (11.7) | .094 | 45.3 (9.5) | .001 |
| TCT, s | 27.0 (–) | 37.0 (19.0) | .548 | 30.0 (9.0) | .533 |
| Fibrinogen, mg/dL | 592 (220) | 387 (125) | <.001 | 432 (123) | <.001 |
Data presented as n (%) or mean ± standard deviation for normally distributed data or as the median with the interquartile range for non‐normally distributed data. Bold values indicates P‐values <0.05.
Abbreviations: aPTT, activated partial thromboplastin time; BMI, body mass index; CRP, C‐Reactive Protein; DLI, Pump‐related percutaneous driveline infection; INR, International Normalized Ratio; INTERMACS, Interagency Registry for Mechanically Assisted Circulatory Support; s, seconds; TCT, Thrombin Clotting Time.
Based on n = 617 laboratory samples collected from the 133 no DLI patients during follow‐up without any symptoms of DLI.
P value reflecting statistical differences between DLI Readmission and DLI no Readmission group.
P value reflecting statistical differences between DLI Readmission and no DLI group.