TABLE 5.
Survival during LVAD support (multivariable Cox proportional hazard model with DLI as time‐dependent covariate)
| Variables | Hazard ratio | Confidence interval (95%) | P value |
|---|---|---|---|
| Age at implant, years | 1.062 | 1.006‐1.112 | .030 |
| Gender, female | 0.306 | 0.072‐1.309 | .110 |
| BMI, kg/m2 | 1.056 | 0.886‐1.259 | .540 |
| Smoking history | 1.629 | 0.698‐3.806 | .259 |
| Diabetes | 1.457 | 0.732‐2.899 | .284 |
| DLI | 1.001 | 0.999‐1.002 | .155 |
| Device | |||
| HeartMate II | ref | ||
| HVAD | 0.734 | 0.302‐1.78 | .494 |
| HeartMate 3 | 0.387 | 0.076‐1.966 | .252 |
| Strategy | |||
| Bridge to candidacy | ref | ||
| Bridge to transplantation | 0.107 | 0.030‐0.379 | .001 |
| Destination therapy | 0.433 | 0.128‐1.130 | .082 |
| Bridge to recovery | – | – | – |
| INTERMACS level | 0.996 | 0.714‐1.389 | .982 |
Bold values indicates P‐values <0.05.
Abbreviations: BMI, body mass index; DLI, pump‐related percutaneous driveline infection; INTERMACS, Interagency Registry for Mechanically Assisted Circulatory Support; LVAD, left ventricular assist device; ref, reference.