Table 1.
Characteristics of Patients
| Variable at baseline |
COT (n = 18) |
NHF (n = 19) |
|---|---|---|
| Age (years) | 63.2 ± 21.8 | 63.7 ± 16.9 |
| Female sex | 15 (83.3) | 16 (84.2) |
| Comorbidities | ||
| Diabetes mellitus | 2 (11.1) | 5 (26.3) |
| Hypertension | 5 (27.8) | 10 (52.6) |
| Hyperlipidemia | 3 (16.7) | 2 (10.5) |
| Chronic kidney disease | 0 (0) | 3 (15.8) |
| Cardiovascular disease | 1 (5.6) | 2 (10.5) |
| Current medication | ||
| ICS | 2 (11.1) | 2 (10.5) |
| LABA | 1 (5.6) | 4 (21.1) |
| SABA | 10 (55.6) | 10 (52.6) |
| ICS + LABA | 13 (72.2) | 15 (78.9) |
| Anticholinergics + SABA | 5 (27.8) | 7 (36.8) |
| Methylxanthine | 2 (11.1) | 4 (21.1) |
| Leukotriene receptor antagonist | 3 (16.7) | 10 (52.6) |
| Procaterol HCl | 3 (16.7) | 4 (21.1) |
| Duration before intervention (minutes) | 70.5 (65–91.5) | 94 (67–103) |
| Oxygen flow before intervention | 4.8 ± 1.5 | 4.9 ± 1.5 |
| Initial vital signs | ||
| Respiratory rate (breaths/min) | 33.6 ± 4.0 | 33.0 ± 4.4 |
| Pulse oximetry (%) | 90.5 ± 1.8 | 90.3 ± 1.8 |
| Heart rate (beats/min) | 114.6 ± 19.2 | 117.6 ± 17.2 |
| Mean arterial pressure (mm Hg) | 111.6 ± 13.3 | 114.6 ± 21.1 |
| Parameter before intervention | ||
| MBS | 7.8 ± 2.0 | 7.8 ± 1.9 |
| NRS | 7.7 ± 2.0 | 7.8 ± 1.9 |
| Dyspnea scale | 5.6 ± 2.1 | 5.6 ± 2.1 |
| Respiratory rate (breaths/min) | 31.8 ± 4.4 | 30.4 ± 4.0 |
| Pulse oximetry (%) | 91.7 ± 1.1 | 91.7 ± 1.9 |
| Heart rate (beats/min) | 108.7 ± 19.7 | 112.7 ± 18.2 |
| Mean arterial pressure (mm Hg) | 106.4 ± 14.6 | 109.5 ± 18.9 |
| Baseline asthma control test score | 14.9 ± 5.1 | 14.6 ± 4.1 |
Data are presented as n (%), mean ± SD, or median (range).
COT = conventional oxygen therapy; ICS = inhaled corticosteroid; MBS = modified Borg scale; LABA = long‐acting beta2‐agonist; NHF = nasal high flow; NRS = numeric rating scale; SABA = short‐acting beta2‐agonist.