TABLE 1.
Pat No. | Almond allergy confirmed by | Sex/Age | Symptoms to almond | Other food allergies | sIgE (kU/L) | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Extract | Pru du 6 | Pru du 8 | Pru du 10 | Bet v 1 | Phl p 12 a | Pru p 3 a | |||||
1 | DBPCFC | M/7 | Pruritus, rash, angioedema, nasal congestion | Peanut, cashew, egg, milk | 7.1 | 6.7 | ≤0.35 | ≤0.35 | 0.6 | 0 | ≤0.35 |
2 | DBPCFC | F/12 | Urticaria | Hazelnut | 183.8 | 148.1 | 13.4 | 75.7 | 25.5 | 0 | ≤0.35 |
3 | DBPCFC | M/8 | Rash | Peanut, cashew, hazelnut, walnut | 125.9 | 69.4 | 159.1 | 33.1 | 2.1 | 0.7 | 3.2 |
4 | DBPCFC | F/4 | Rash | Peanut, milk, wheat | 7.5 | 11.5 | ≤0.35 | 0.9 | ≤0.35 | ≤0.35 | ≤0.35 |
5 | DBPCFC | F/5 | Angioedema | Peanut, egg, walnut | 6.3 | 5.9 | ≤0.35 | ≤0.35 | 1.0 | ≤0.35 | ≤0.35 |
6 | DBPCFC | F/10 | Urticaria | Cashew, hazelnut, walnut | 0.4 | ≤0.35 | ≤0.35 | ≤0.35 | 21.8 | ≤0.35 | ≤0.35 |
7 | DBPCFC | M/6 | Urticaria, rash | Peanut, cashew, hazelnut, walnut | 8.0 | 6.5 | ≤0.35 | 1.0 | ≤0.35 | 1.7 | 1.1 |
8 | DBPCFC | F/11 | Urticaria | Peanut, cashew, hazelnut, walnut | 317.2 | 181.7 | 44.5 | 24.2 | ≤0.35 | ≤0.35 | ≤0.35 |
9 | DBPCFC | F/7 | Urticaria | Egg | 2.7 | 2.0 | 1.3 | ≤0.35 | ≤0.35 | ≤0.35 | ≤0.35 |
10 | DBPCFC | F/12 | Urticaria | Cashew, hazelnut, walnut | 12.6 | 3.6 | ≤0.35 | 14.4 | 14.2 | ≤0.35 | ≤0.35 |
11 | DBPCFC | F/9 | Throat tightness, abdominal pain | None | 27.4 | 8.7 | 1.5 | 4.0 | 3.6 | ≤0.35 | ≤0.35 |
12 | DBPCFC | M/12 | Urticaria, angioedema | None | 2.2 | 1.1 | 1.3 | ≤0.35 | 6.0 | 1.5 | ≤0.35 |
13 | DBPCFC | M/15 | Urticaria | None | 21.1 | 6.0 | 54.1 | 2.0 | 33.4 | ≤0.35 | ≤0.35 |
14 | DBPCFC | M/9 | Urticaria | None | 73.7 | 81.1 | 0.5 | 95.1 | 18.7 | ≤0.35 | ≤0.35 |
15 | positive history | Angioedema | Peanut, hazelnut, walnut, cashew, pecan, | 38.2 | 8.7 | ≤0.35 | 0.9 | ≤0.35 | ≤0.35 | 9.6 | |
16 | positive history | M/4 | Urticaria | Peanut, cashew, pistachio | 19.3 | 22.9 | ≤0.35 | 3.3 | 7.0 | ≤0.35 | ≤0.35 |
17 | positive history | F/18 | Angioedema, oropharyngeal pruritus and mild erythema | Peanut | 1.6 | ≤0.35 | ≤0.35 | 0.4 | ≤0.35 | 3.1 | 3.4 |
18 | positive history | F/48 | Angioedema, oropharyngeal pruritus and mild erythema | Peanut, walnut | ≤0.35 | ≤0.35 | ≤0.35 | ≤0.35 | 2.6 | ≤0.35 | 2.1 |
IgE specific to Bet v 1, Phl p 12, and Pru p 3 was measured as representatives of an almond Bet v 1‐homologue, almond profilin, and almond nsLTP, respectively.