TABLE 2.
Almond‐tolerant (19‐36) and atopic (37‐40) patients: clinical characteristics and IgE sensitization pattern as determined by quantitative ELISA
| Pat No. | Almond allergy a | Sex/Age | Symptoms to almond | Other food allergies | sIgE (kU/L) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Extract | Pru du 6 | Pru du 8 | Pru du 10 | Bet v 1 b | Phl p 12 b | Pru p 3 b | |||||
| 19 | No | F/31 | None | Peanut, hazelnut, walnut, poppy seed | 4.2 | ≤0.35 | ≤0.35 | ≤0.35 | 17.1 | ≤0.35 | ≤0.35 |
| 20 | No | F/22 | None | Peanut, hazelnut, lupine, peach, kiwi | 1.4 | 0.9 | ≤0.35 | 3.3 | ≤0.35 | ≤0.35 | ≤0.35 |
| 21 | No | M/7 | None | Peanut, hazelnut, walnut, milk | 3.2 | 11.3 | 0.41 | 1.8 | 21.3 | ≤0.35 | ≤0.35 |
| 22 | No | M/18 | None | Peanut | ≤0.35 | 1.0 | ≤0.35 | ≤0.35 | 4.3 | ≤0.35 | ≤0.35 |
| 23 | No | M/17 | None | Hazelnut, walnut, milk, egg | ≤0.35 | ≤0.35 | ≤0.35 | ≤0.35 | 25.4 | ≤0.35 | ≤0.35 |
| 24 | No | M/20 | None | Hazelnut, macadamia | 0.4 | ≤0.35 | ≤0.35 | 0.6 | ≤0.35 | ≤0.35 | ≤0.35 |
| 25 | No | F/27 | None | Peanut, walnut | 2.0 | 1.6 | ≤0.35 | 0.9 | 6.0 | ≤0.35 | ≤0.35 |
| 26 | No | F/9 | None | Peanut, hazelnut, walnut, cashew | 4.1 | ≤0.35 | ≤0.35 | 1.4 | ≤0.35 | ≤0.35 | ≤0.35 |
| 27 | No | F/37 | None | Hazelnut walnut, | 0.8 | ≤0.35 | ≤0.35 | 0.7 | 4.4 | ≤0.35 | 16.3 |
| 28 | No | M/28 | None | Peanut | 0.6 | ≤0.35 | ≤0.35 | ≤0.35 | 3.1 | ≤0.35 | ≤0.35 |
| 29 | No | F/31 | None | Peanut, hazelnut, walnut | ≤0.35 | ≤0.35 | ≤0.35 | ≤0.35 | 7.9 | ≤0.35 | ≤0.35 |
| 30 | No | M/10 | None | Peanut, apple | ≤0.35 | ≤0.35 | ≤0.35 | 0.5 | 6.7 | ≤0.35 | ≤0.35 |
| 31 | No | F/26 | None | Peanut, hazelnut, walnut | 0.8 | ≤0.35 | ≤0.35 | ≤0.35 | 2.0 | ≤0.35 | ≤0.35 |
| 32 | No | F/21 | None | Peanut, hazelnut, walnut | ≤0.35 | ≤0.35 | ≤0.35 | ≤0.35 | 15.3 | ≤0.35 | ≤0.35 |
| 33 | No | F/42 | None | Walnut | 0.45 | ≤0.35 | ≤0.35 | ≤0.35 | ≤0.35 | ≤0.35 | 3.4 |
| 34 | No | M/18 | None | Peanut | ≤0.35 | ≤0.35 | ≤0.35 | ≤0.35 | 0.9 | ≤0.35 | ≤0.35 |
| 35 | No | F/48 | None | Hazelnut, walnut | 0.4 | ≤0.35 | ≤0.35 | ≤0.35 | ≤0.35 | ≤0.35 | ≤0.35 |
| 36 | No | F/30 | None | Peanut, hazelnut | 0.5 | ≤0.35 | ≤0.35 | ≤0.35 | 0.5 | ≤0.35 | ≤0.35 |
| 37 | No | F/48 | None | None | ≤0.35 | ≤0.35 | ≤0.35 | ≤0.35 | 0.6 | ≤0.35 | ≤0.35 |
| 38 | No | M/29 | None | None | ≤0.35 | ≤0.35 | ≤0.35 | ≤0.35 | 25.5 | ≤0.35 | ≤0.35 |
| 39 | No | M/32 | None | None | ≤0.35 | ≤0.35 | ≤0.35 | ≤0.35 | 2.1 | ≤0.35 | ≤0.35 |
| 40 | No | M/50 | None | None | ≤0.35 | ≤0.35 | ≤0.35 | ≤0.35 | ≤0.35 | ≤0.35 | ≤0.35 |
a
Based on a detailed questionnaire, all subjects consumed almonds regularly without allergic symptoms.
b
IgE specific to Bet v 1, Phl p 12, and Pru p 3 was measured as representatives of an almond Bet v 1‐homologue, almond profilin, and almond nsLTP, respectively.