Skip to main content
. 2021 Jun 16;12(16):5013–5024. doi: 10.7150/jca.58023

Figure 2.

Figure 2

HNF1A increased the proliferation and invasion of TE1 and KYSE150 ESCC cells, and reduced their radiosensitivity. (A) Cell proliferation was detected by the CCK8 assay. (B) The radiosensitivity of ESCC cells was measured by clone formation assay. (C) Transwell assay was used to detect the ability of cell invasion (magnification, x200). (D) The EMT-related proteins and MMP2/MMP9 proteins were detected by western blot. A comparison with the NC group is indicated by asterisks *P < 0.05, **P < 0.01 and ***P < 0.001; a comparison with the corresponding non-irradiated group is indicated by triangles ▲ P < 0.05 and ▲▲P < 0.01. CCK-8: Cell Counting Kit-8; HNF1A: hepatocyte nuclear factor 1-alpha; IR: irradiation; ESCC: esophageal squamous cell carcinoma; EMT: epithelial mesenchymal transition.