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Effect of SAR247799 (1 and 5 mg), sildenafil (50 mg), or placebo on heart rate (A) and lymphocytes (B) in type‐2 diabetes patients. Heart rate and lymphocytes expressed on each day (D1–D28) at time points associated with maximal pharmacodynamic effects (4 and 6.5 h, respectively). Mean ± standard error of the mean; P values shown when < .05 (repeated‐measure model as described under Methods)
