Table 3.
Predictive value of RV longitudinal strain in heart failure.
| References | Sample size | RV free-wall/global GLS cut-off | Follow-up period (months) | Main findings |
|---|---|---|---|---|
| Cameli et al. (45) | 590 | −15% | 18 ± 11 | Free-wall RV longitudinal strain was the strongest predictor of combined outcome, even stronger than LV global longitudinal strain, which support importance of RV strain in prognostic stratification in HF patients. |
| Hamada-Harimura et al. (46) | 618 | −13.1% | 14 | In patients with acute HF decompensation RV free-wall longitudinal strain was an independent predictor of cardiac events (CV death or unplanned hospitalization due to HF worsening). |
| Vizzardi et al. (47) | 60 | −18% | 32 ± 13 | RV free-wall longitudinal strain, but not TAPSE, FAC, and s′, was independent predictor of CV events (hospitalization and CV mortality) in HFrEF patients. |
| Carluccio et al. (48) | 200 | −15.3% | 28 | RV free-wall longitudinal strain was a better predictor than TAPSE in HFrEF patients with the best discriminatory value of RV free-wall longitudinal strain. |
| Kusunose et al. (49) | 58 | −16% | 5 | RV longitudinal strain in HFrEF patients was a good predictor of functional capacity improvement (VO2 peak) in HFrEF patients who were referred for cardiac rehabilitation. |
| Motoki et al. (11) | 171 | −14.8% | 60 | RV free-wall strain was a predictor of adverse CV events (death, cardiac transplantation, and hospitalization due to HF) independently of age, LVEF, tricuspid s′, E/e′ septal, and right atrial volume index in a population of patients with chronic HFrEF. |
| Houard et al. (50) | 266 | −19% | 56 | Echocardiography-derived RV free-wall longitudinal strain was a better predictor of overall and CV mortality than TAPSE, FAC, and CMR-derived RVEF, RV longitudinal strain. |
| Carluccio et al. (51) | 288 | −15.3% | 30 ± 23 | Global RV longitudinal strain did not remain independent predictor of composite outcome (all-cause death/HF-related hospitalization) in the models that included LV parameters and other RV parameters, whereas RV free-wall strain remained an independent predictor in all models. |
| Lisi et al. (52) | 27 | – | – | RV free-wall strain had the highest diagnostic accuracy for detecting severe myocardial fibrosis, much better than TAPSE, right atrial longitudinal strain and VO2 peak. |
| Park et al. (53) | 799 | −12% | 32 | In patients with acute HF was found that global RV longitudinal strain was a predictor of all-cause mortality regardless of LV global longitudinal strain and clinical characteristics. |
| Bosch et al. (54) | 657 | −15.3% | 24 | The authors reported that RV free-wall longitudinal strain, sPAP and their ratio were independent predictors of composite endpoint (mortality and HF hospitalization) in the whole population of HF patients. |
CMR, cardiac magnetic resonance; CV, cardiovascular; FAC, fractional area change; GLS, global longitudinal strain; HF, heart failure; HFpEF, heart failure with preserved ejection fraction; HFrEF, heart failure with reduced ejection fraction; LV, left ventricle; RV, right ventricle; s′, systolic velocity of the lateral segment of tricuspid annulus; sPAP, systolic pulmonary pressure; TAPSE, tricuspid annular plane systolic excursion.