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. 2021 Jun 17;9:649755. doi: 10.3389/fcell.2021.649755

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Copyright © 2021 Xu, Wang, Pang, Cao, Wang, Yu, Xu, Xu, Wang, Lu and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The property and functional analysis of the core component. (A) The largest component of the core dysregulated ceRNA interactions. (B) The property of edge linked to lncRNAs in the core component. The assignment of lncRNAs was sorted by node degree in the core component. Only show the lncRNAs with a degree of more than 10 in the core component. (C,D) The comparison of the percent of cancer-related ceRNAs and the number of common miRNAs between the core component ceRNAs and single dysregulated network. (E,F) The biological process and KEGG pathway enriched by the genes in the core component.