Table 1.
Clinical and demographic characteristics at baseline
| Exenatide (n = 109) | Placebo (n = 54) | P | |
|---|---|---|---|
| Sex (% male) | 95 | 98 | 0.40 |
| Race (% white) | 90 | 80 | 0.09 |
| Age (years) | 63 ± 8 | 64 ± 7 | 0.90 |
| BMI (kg/m2) | 33 ± 6 | 33 ± 6 | 0.50 |
| Obesity (%) | 71 | 63 | 0.40 |
| Diabetes duration (years) | 6 ± 4 | 6 ± 4 | 0.40 |
| Fasting glucose (mg/dL) | 155 ± 45 | 161 ± 53 | 0.30 |
| HbA1c (%) | 7.8 ± 1.2 | 8.1 ± 1.3 | 0.20 |
| HbA1c (mmol/L) | 62 ± 14 | 65 ± 14 | 0.20 |
| Systolic BP (mmHg) | 135 ± 17 | 141 ± 18 | 0.03 |
| Diastolic BP (mmHg) | 81 ± 11 | 85 ± 13 | 0.02 |
| History of hypertension (%) | 94 | 87 | 0.20 |
| History of CVD (%) | 21 | 22 | 0.80 |
| Smoking (%) | 15 | 22 | 0.30 |
| Statins (%) | 80 | 83 | 0.70 |
| Fasting triglycerides (mg/dL) | 170 ± 108 | 166 ± 74 | 0.80 |
| Fasting cholesterol (mg/dL) | 149 ± 32 | 160 ± 39 | 0.11 |
| HDL cholesterol (mg/dL) | 43 ± 10 | 43 ± 10 | 0.90 |
| LDL cholesterol (mg/dL) | 75 ± 24 | 84 ± 34 | 0.10 |
Data are means ± SD unless otherwise indicated. P values indicate between-group comparison by Student t test (for continuous variables) or by χ2 test (for categories). BP, blood pressure.