Table 1.
Characteristics of patients with new-onset diabetes
| 2018 | 2019 | 2020 | P value | |
|---|---|---|---|---|
| Age, years (mean ± SD) | 13.5 ± 2.4 | 14.2 ± 2.5 | 14.0 ± 2.6 | 0.3462 |
| HbA1c, % (IQR) | 10.3 (5.0) | 8.3 (5.4) | 10.4 (4.1) | 0.0267 |
| HbA1c, mmol/mol (IQR) | 89 (31) | 67 (36) | 90 (21) | |
| %BMIp95 | 128 ± 31 | 129 ± 28 | 135 ± 31 | 0.2765 |
| Ethnicity, n (%) | 0.0065 | |||
| Latinx | 36 (82) | 44 (67) | 45 (55) | |
| Non-Latinx | 7 (16) | 7 (11) | 13 (16) | |
| Unknown | 1 (2) | 15 (22) | 24 (29) | |
| Race, n (%) | NA | |||
| White | 7 (16) | 16 (24) | 15 (18) | |
| Black | 3 (7) | 3 (5) | 7 (9) | |
| Asian | 2 (5) | 2 (3) | 2 (2) | |
| Native American/Eskimo | 0 (0) | 0 (0) | 1 (1) | |
| Other | 31 (70) | 35 (53) | 47 (57) | |
| Unknown | 1 (2) | 10 (15) | 10 (12) | |
| New-onset patients, n (% female) | 44† (57) | 66 (55) | 82 (46) | NA |
| DKA, n (%) | 4 (9) | 2 (3) | 16 (20) | 0.0290 |
| Severe DKA (DKA/new), n (%) | 0/44 (0) | 0/66 (0) | 2/82 (2) | NA |
| Pancreatic antibody, n (%) | NA | |||
| Positive | 2 (5) | 2(3) | 1 (1) | |
| Negative | 35 (80) | 61(92) | 74 (90) | |
| Not done | 7 (16) | 3(5) | 7 (9) | |
| SARS-CoV2 prevalence in DKA‡ | NA | |||
| SARS-CoV2 PCR+, n (%) | — | — | 0/14 (0) | |
| SARS-CoV2 IgG, n (%) | — | — | 2/6 (33) |
Bold P values are statistically significant (P < 0.05). %BMIp95, excess percent of the 95th percentile. NA, not applicable.
†
No information was available on whether one patient was in DKA at diagnosis.
‡
Only subjects admitted as inpatients to CHLA for DKA were tested.