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. 2021 Jul 1;2021(7):CD003586. doi: 10.1002/14651858.CD003586.pub4

Summary of findings 5. Movement interventions compared to any control for spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury.

Movement interventions compared to any control for spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury
Patient or population: spatial neglect or inattention following stroke and other adult‐acquired non‐progressive brain injury
Setting: inpatient or community rehabilitation
Intervention: movement interventions
Comparison: any control
Outcomes Relative effect
(95% CI) No. of participants
(studies)
Certainty of the evidence
(GRADE) Comments
Primary outcome
Activities of daily living: effects persisting at least 1 month post intervention No studies  
Secondary outcomes
Activities of daily living: immediate effects SMD 0.57 higher (0.09 higher to 1.04 higher) 75
(3 RCTs)
⊕⊝⊝⊝
Very lowa,b,c Evidence suggests possible benefit from intervention
Neglect outcomes: effects persisting at least 1 month post intervention No studies  
Neglect outcomes: immediate effects SMD 0.57 higher (0.04 higher to 1.10 higher) 58
(2 RCTs)
⊕⊝⊝⊝
Very lowa,b,c Evidence suggests possible benefit from intervention
Adverse events No studies  
CI: confidence interval; RCT: randomised controlled trial; SMD: standardised mean difference.
GRADE Working Group grades of evidence.High certainty: we are very confident that the true effect lies close to that of the estimate of the effect.
Moderate certainty: we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different.
Low certainty: our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect.
Very low certainty: we have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect.

aOverall, studies contributing to this analysis had limitations regarding risk of bias sufficient to lower certainty regarding the estimate of effect and were downgraded once.

bDowngraded twice for serious imprecision (very small numbers of participants).

cDowngraded once for indirectness. Studies included only participants with recent‐onset stroke.