Table 1.
Columbia | Houston | Aachen | |||||||
---|---|---|---|---|---|---|---|---|---|
Total Patients 310 | - | Total Patients 38 | - | Total Patients 40 | - | ||||
DCI+ | DCI− | p value | DCI+ | DCI− | p value | DCI+ | DCI− | p value | |
n=101 | n=209 | n=12 | n=26 | n=11 | n=29 | ||||
Age, y, median (IQR) | 54 (45-65) | 57 (46-65) | 0.765 | 59 (49-65.5) | 0.137 | ||||
50 (44-62) | 56 (47-66) | 0.033* | 53 (49-60) | 59 (45-70) | 0.285 | 52 (48-60) | 60 (53-66) | 0.055 | |
Female Gender, n (%) | 218 (70.3) | 28 (73.7) | 0.85 | 27 (67.5) | 0.716 | ||||
81 (80.2) | 137 (65.6) | 0.008* | 12 (100.0) | 16 (61.5) | 0.016* | 9 (81.8) | 18 (62.1) | 0.286 | |
Hispanic Ethnicity, n (%) | 99 (31.9) | 12 (31.6) | 1 | 0 (0.0) | N/A | ||||
30 (29.7) | 69 (33.0) | 0.604 | 3 (25.0) | 9 (34.6) | 0.714 | 0 (0.0) | 0 (0.0) | 1 | |
Tobacco Use, n (%) | 166 (53.6) | 20 (52.6) | 1 | 15 (37.5) | 0.065 | ||||
55 (54.5) | 111 (53.1) | 0.713 | 9 (75.0) | 11 (42.3) | 0.086 | 5 (45.5) | 10 (34.5) | 0.716 | |
Hypertension History | 146 (47.1) | 27 (71.0) | 0.006* | 16 (40.0) | 0.5 | ||||
39 (38.6) | 107 (51.2) | 0.04* | 11 (91.7) | 16 (61.5) | 0.121 | 7 (63.6) | 9 (31.0) | 0.08 | |
HH, 4 - 5, n (%) | 88 (28.4) | 19 (50.0) | 0.008* | 15 (37.5) | 0.269 | ||||
40 (39.6) | 48 (23.0) | 0.003* | 5 (41.7) | 14 (53.8) | 0.728 | 7 (63.6) | 8 (27.6) | 0.065 | |
WFNS, 4 - 5, n (%) | 121 (39.0) | 22 (57.9) | 0.035* | 17 (42.5) | 0.732 | ||||
50 (49.5) | 71 (34.0) | 0.009* | 7 (58.3) | 15 (57.7) | 1 | 7 (63.6) | 10 (34.5) | 0.153 | |
GCS, median (IQR) | 14 (8-15) | 8 (5-14) | <0.001* | 13 (7-15) | 0.101 | ||||
13 (6-15) | 15 (9-15) | <0.001* | 9 (6-13) | 8 (5-14) | 0.95 | 7 (6-13) | 13 (8-15) | 0.053 | |
mFS, 3 - 4, n (%) | 120 (38.7) | 38 (100.0) | <0.001* | 20 (50.0) | 0.175 | ||||
38 (37.6) | 82 (39.2) | 0.805 | 12 (100.0) | 26 (100.0) | 1 | 9 (81.8) | 11 (37.9) | 0.031* | |
mFS 0, n (%) | 0 (0.0) | 15 (7.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |||
mFS 1, n (%) | 15 (14.9) | 41 (19.6) | 0 (0.0) | 0 (0.0) | 2 (18.2) | 12 (41.4) | |||
mFS 2, n (%) | 48 (47.5) | 71 (34.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 6 (20.7) | |||
mFS 3, n (%) | 32 (31.7) | 73 (34.9) | 6 (50.0) | 19 (73.1) | 4 (36.4) | 3 (10.34) | |||
mFS 4, n (%) | 6 (5.9) | 9 (4.3) | 6 (50.0) | 7 (26.9) | 5 (45.5) | 8 (27.6) | |||
Vasopressor Use, n (%) | 66/242 (27.3) | 20 (52.6) | 0.002* | 37 (92.5) | <0.001* | ||||
47/78 (60.3) | 19/164 (11.6) | <0.001* | 10 (83.3) | 10 (38.5) | 0.015* | 11 (100) | 26 (89.7) | 0.548 | |
Cerebral Edema, n (%) | 176 (56.77) | 10 (26.32) | <0.001 | 8 (20) | <0.0001 | ||||
76 (75.2) | 100 (47.8) | <0.0001* | 4 (33.3) | 6 (23.1) | 0.694 | 4 (36.4) | 4 (13.8) | 0.182 | |
Fever >38.6°C, n (%) | 126 (40.65) | 26 (68.42) | 0.002* | 34 (85) | <0.0001* | ||||
54 (53.5) | 72 (34.4) | 0.002* | 8 (66.7) | 18 (69.2) | 1 | 11 (100) | 23 (79.3) | 0.162 | |
Hydrocephalus, n (%) | 143 (46.1) | 26 (68.4) | 0.010* | 34 (85.0) | <0.0001* | ||||
61 (60.4) | 82 (39.2) | <0.001* | 9 (75.0) | 17 (65.4) | 0.714 | 11 (100) | 23 (79.3) | 0.162 | |
Pulmonary Edema, n (%) | 51 (16.5) | 9 (23.7) | 0.260 | 10 (25.0) | 0.186 | ||||
27 (26.7) | 24 (11.5) | 0.001* | 4 (33.3) | 5 (19.2) | 0.423 | 3 (27.3) | 7 (24.1) | 1 | |
Seizures, n (%) | 32 (10.3) | 3 (7.9) | 0.782 | 11 (27.5) | 0.004* | ||||
12 (11.9) | 20 (9.6) | 0.553 | 1 (8.3) | 2 (7.6) | 1 | 3 (27.3) | 8 (27.6) | 1 | |
In-Hospital Mortality, n (%) | 34 (11.0) | 3 (7.9) | 0.781 | 9 (22.5) | 0.068 | ||||
8 (7.9) | 26 (12.4) | 0.253 | 0 (0.0) | 3 (11.54) | 0.538 | 5 (45.5) | 4 (13.8) | 0.083 | |
LOS, d, median (IQR) | 14.9 (11-22) | 13 (10-17) | 0.103 | 14.5 (11-20) | 0.474 | ||||
22 (17-30) | 12 (10-16) | <0.0001* | 18 (16-21) | 12 (9-14) | 0.004* | 18 (15-25) | 14 (9-18) | 0.022* | |
mRS at Discharge, 3 - 6, n (%) | 195 (62.9) | 35 (92.1) | <0.001* | 24 (60.0) | 0.730 | ||||
89 (88.1) | 106 (50.7) | <0.0001* | 10 (83.3) | 25 (96.2) | 0.229 | 9 (81.8) | 15 (51.7) | 0.148 | |
mRS at 3 Months, 3 - 6, n (%) | 92/238 (38.7) | 16/29 (55.2) | 0.108 | 15/27 (55.6) | 0.101 | ||||
40/74 (54.1) | 52/164 (31.7) | 0.001* | 4/11 (36.4) | 12/18 (66.7) | 0.143 | 6/9 (22.2) | 9/18 (50.0) | 0.683 | |
mRS at 12 Months, 3 - 6, n (%) | 93/229 (40.6) | 8/14 (57.1) | 0.268 | 11/19 (57.9) | 0.154 | ||||
36/70 (51.4) | 57/159 (35.8) | 0.029* | 2/4 (50.0) | 6/10 (60.0) | 1 | 6/7 (85.7) | 5/12 (41.7) | 0.147 |
statistically significant