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. 2021 Jun 17;12:638694. doi: 10.3389/fimmu.2021.638694

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Copyright © 2021 Chauhan, Rathore, Sachan, Lacroix-Desmazes, Gupta, Awasthi, Vrati and Kalia

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Upregulation of maturation markers in JEV infected moDCs. (A) Heatmap showing transcriptional upregulation of DC maturation and other co-stimulatory markers in mock vs JEV-infected condition in the three donors. (B, C) The cell surface expression of DC maturation and co-stimulatory markers was quantified by flow cytometry in mock/(5 MOI) JEV-infected moDCs at 24 hpi. Data for each donor is shown as median fluorescence intensity (MFI) with the mean (n = 13 donors). *p < 0.05; **p < 0.01 (Wilcoxon matched-pairs signed-rank test). (C) Representative flow cytometry profile of one donor. Ns, not significant.