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JEV-infected moDCs lead to expansion of Tregs in mixed lymphocyte reactions. CD4+ T cells were co-cultured with mock/JEV infected moDCs at 10:1 (T:DC) ratio in an allogenic co-culture assay for 4 days. mRNA levels of T-subset specific transcription factors T-BET, GATA3, FOXP3 and RORγt were analysed through qRT-PCR. Plotted are values and mean from 4 independent experiments shown as log10 expression normalized to mock-treated moDCs.
