Table 1.
Preoperative backgrounds and comparison of backgrounds based on FIB-4 index.
| Variables | Overall Mean ± SD (%) [n = 556] | High FIB-4 index Mean ± SD (%) [n = 495] | Low FIB-4 index Mean ± SD (%) [n = 61] | p-Value |
|---|---|---|---|---|
| Age, y | 64.34 ± 10.72 | 65.86 ± 9.46 | 52 ± 12.35 | <0.001 |
| Gender | 0.17 | |||
| Male | 422 (75.9) | 380(76.8) | 42(68.9) | |
| Female | 134 (24.1) | 115(23.2) | 19(31.1) | |
| BMI, kg/m2 | 22.43 ± 3.01 | 22.43 ± 3.01 | 22.49 ± 3.06 | 0.78 |
| HB (g/L) | 121.23 ± 22.05 | 122.41 ± 21.04 | 111.64 ± 27.33 | 0.003 |
| ALB (g/L) | 38.19 ± 4.42 | 38.14 ± 4.39 | 38.63 ± 4.66 | 0.44 |
| PLT (10^9/L) | 245.62 ± 82.40 | 233.32 ± 70.70 | 345.49 ± 101.33 | 0.003 |
| ALT | 18.96 ± 14.73 | 18.37 ± 12.83 | 23.77 ± 25.00 | <0.001 |
| AST | 22.78 ± 10.02 | 23.23 ± 9.99 | 19.18 ± 9.60 | 0.59 |
| FIB-4 | 1.65 ± 0.93 | 1.77 ± 0.91 | 0.65 ± 0.12 | <0.001 |
| ASA | <0.001 | |||
| 1-2 | 460(82.7) | 403(81.4) | 57(93.44) | |
| ≥3 | 96(17.3) | 92(18.6) | 4(6.56) | |
| Charlson score | 0.07 | |||
| 0 | 282(50.7) | 243(49.1) | 39(63.9) | |
| 1-2 | 252(45.3) | 231(46.7) | 21(34.4) | |
| 3-6 | 22(4.0) | 21(4.2) | 1(1.6) | |
| NRS | 0.10 | |||
| 1-2 | 343(61.7) | 302(61.0) | 41(67.2) | |
| 3-4 | 172(30.9) | 153(30.9) | 19(31.1) | |
| 5-6 | 41(7.4) | 40(8.1) | 1(1.6) | |
| Surgical history | 0.50 | |||
| No | 443(79.7) | 392(79.2) | 51(83.6) | |
| Yes | 113(20.3) | 103(20.8) | 10(16.4) | |
| Abdominal surgery history | 0.31 | |||
| No | 484(87.1) | 428(86.5) | 56(91.8) | |
| Yes | 72(12.9) | 67(13.5) | 5(8.2) | |
| Preoperative diabetes | 0.83 | |||
| No | 492(88.5) | 437(88.3) | 55(90.2) | |
| Yes | 64(11.5) | 58(11.7) | 6(9.8) | |
| Hypertension | 0.09 | |||
| No | 413(74.3) | 362(73.1) | 51(83.6) | |
| Yes | 143(25.7) | 133(26.9) | 10(16.4) | |
| Hepatic diseases | 1 | |||
| No | 534(96.0) | 475(96.0) | 59(96.7) | |
| Yes | 22(4.0) | 20(4.0) | 2(3.3) | |
| Laparoscopic surgery | 1 | |||
| No | 410(73.7) | 365(73.7) | 45(73.8) | |
| Yes | 146(26.3) | 130(26.3) | 16(26.2) | |
| Surgical procedure | 0.05 | |||
| SG | 345(62.1) | 300(60.6) | 45(73.8) | |
| TG | 211(37.9) | 195(39.4) | 16(26.2) | |
| Type of reconstruction | 0.10 | |||
| B-I | 220(39.6) | 195(39.4) | 25(41.0) | |
| B-II | 91(16.4) | 77(15.6) | 14(23.0) | |
| Roux-en-Y | 245(44.1) | 223(45.1) | 22(36.1) | |
| Combined resection | 0.64 | |||
| No | 507(91.2) | 450(90.9) | 57(93.4) | |
| Yes | 49(8.8) | 45(9.1) | 4(6.6) | |
| Surgical durations (min) | 203.92 ± 53.61 | 204.13 ± 53.65 | 0.94 | |
| Histologic type | 0.44 | |||
| Undifferentiated | 148(26.6) | 129(26.1) | 19(31.1) | |
| Differentiated | 408(73.4) | 366(73.9) | 42(68.9) | |
| Tumor site | 0.62 | |||
| Upper | 73(13.1) | 64(12.9) | 9(14.8) | |
| Middle | 111(20.0) | 101(20.4) | 10(16.4) | |
| Low | 351(63.1) | 310(62.6) | 41(67.2) | |
| Mixed | 21(3.8) | 20(4.0) | 1(1.6) | |
| T stage | 0.04 | |||
| 1-2 | 205(36.9) | 190(38.4) | 15(24.6) | |
| 3-4 | 351(63.1) | 305(61.6) | 46(75.4) | |
| N stage | 0.29 | |||
| 0 | 249(44.8) | 221(44.6) | 28(45.9) | |
| 1 | 99(17.8) | 93(18.8) | 6(9.8) | |
| 2 | 111(20.0) | 97(19.6) | 14(23.0) | |
| 3 | 97(17.4) | 84(17.0) | 13(21.3) | |
| TNM stage | 0.34 | |||
| I | 179(32.2) | 164(33.1) | 15(24.6) | |
| II | 119(21.4) | 103(20.8) | 16(26.2) | |
| III | 258(46.4) | 228(46.1) | 30(49.2) | |
| Postoperative complications | 0.25 | |||
| NO | 370(66.5) | 325(65.7) | 45(73.8) | |
| YES | 186(33.5) | 170(34.3) | 16(26.2) |
SD, standard deviation; BMI, body mass index; HB, hemoglobin; ALB, albumin; PLT, platelet; ALT, alanine aminotransferase; AST, aspartate aminotransferase; FIB-4, Fibrosis-4; ASA, American Society of anesthesiologists; NRS, Nutritional Risk Screening; SG, subtotal gastrectomy; TG, total gastrectomy.