Table 2.
Prognostic factors for overall survival.
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | |
| FIB-4 (low/high) | 2.54(1.22-5.28) | 0.01* | 4.65(1.07-4.29) | 0.031* |
| Gender | 1.54(0.98-2.43) | 0.06 | ||
| Age (≧70/<70) | 2.44(1.67-3.57) | <0.01* | 4.66(1.03-2.00) | 0.031* |
| BMI (≧25/<25) | 0.62(0.37-1.05) | 0.09 | ||
| ASA | 0.03* | |||
| NRS | <0.01* | |||
| Charlson score | <0.01* | |||
| Previous surgery | 1.33(0.86-2.08) | 0.20 | ||
| Previous abdominal surgery | 1.38(0.81-2.32) | 0.23 | ||
| HB (≧100g/L/<100 g/L) | 1.48(0.94-2.32) | 0.09 | ||
| ALB(≧35/<35 g/L) | 0.43(0.28-0.64) | <0.01* | ||
| Hepatic diseases | 1.44(0.59-3.49) | 0.42 | ||
| Tumor site | <0.01* | 14.96 | <0.01* | |
| Upper | 1 | |||
| Middle | 0.01(0.59-1.82) | 0.913 | ||
| Low | 2.09(0.87-2.54) | 0.148 | ||
| Mixed | 11.02(1.59-5.99) | <0.01* | ||
| Laparoscopic surgery | 0.37(0.23-0.61) | <0.01* | ||
| Surgical procedure (SG/TG) | 3.15(2.15-4.61) | <0.01* | 5.59(1.18-5.94) | 0.018* |
| Combined resection | 3.15(1.74-5.70) | <0.01* | ||
| Type of reconstruction | <0.01* | 5.89 | 0.053 | |
| Roux-en-Y | 1 | |||
| B-I | 0.01(0.45-2.36) | 0.934 | ||
| B-II | 2.19(0.81-4.38) | 0.139 | ||
| Surgical durations | 1.06(0.74-1.54) | 0.74 | ||
| T stage | 7.06(4.16-11.98) | <0.01* | ||
| N stage | <0.01* | |||
| TNM stage | <0.01* | 52.77 | <0.01* | |
| I | 1 | |||
| II | 8.72(1.46-6.53) | <0.01* | ||
| III | 40.04(4.37-16.40) | <0.01* | ||
| Histologic type | 0.89(0.58-1.35) | 0.67 | ||
| Postoperative complications | <0.01* | 5.24(1.06-2.04) | 0.022* | |
HR, hazard ratio; CI, confidence interval; FIB-4, Fibrosis-4; BMI, body mass index; ASA, American Society of anesthesiologists; NRS, Nutritional Risk Screening; HB, hemoglobin; ALB, albumin; SG, subtotal gastrectomy; TG, total gastrectomy.
*Statistically significant (P < 0.05).