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. 2017 Feb 3;24(1):40–50. doi: 10.1080/10717544.2016.1228715

Figure 5.

Figure 5.

Typical kidney tissue alterations verified in rats treated with AMB or its equivalent dose as 1.0 mg/kg of body weight as iv administration of different Amb-PLGAPEG copolymer. 1) normal kidney tissue; 2,3,4) Fungizone® f1 and f2, respectively, varying degree of nephrotoxicity necrosis related to iv administration of iv doses (5 mg/kg).