TABLE 3.

Biological processes regulated by the commonly regulated genes following MSTN inhibition.

Biological Process	Genes
Signal transduction
Insulin/IGF-I signaling	Pak1, Igfbp5, Tbc1d1
Smad signaling	Skil
EGFR signaling	Ptpn3
MAPK signaling	Dusp26
CGRP signaling	Ramp1
NO-mediated signaling	Nos1
Cell organization
Mitochondrial organization	Gdap1
Myofilaments and Cytoskeleton	Mybph, Lmod2, Itgb5
Proteostasis
Proteosynthesis	Xrcc5, Atp1b4
Protein folding	Hspb8
Proteolysis	Asb15
Detoxification and Cytoprotection
Detoxification of selenium compounds	Inmt
Regulation of NO generation	Ddah1
Transport
Sodium ion transport	Fxyd6

EGFR, Epidermal growth factor receptor; MAPK, Mitogen-activated protein kinase; CGRP, Calcitonin gene-related peptide; NO, Nitric oxide.