Table 8.
Summary of treatment studies and related information resources.
| Treatment Studies | ||
|---|---|---|
| Reference | Approach | Key Findings |
| Henry et al. (2018) | Repeated rehearsal of scripts with clinician plus intensive home practice with audiovisual model (script training, guided by Youmans et al. (2011)) | • Improved production of scripted words for trained topics and improved intelligibility for trained and untrained topics in 10 individuals with mild-moderate nfPPA, all who had AOS • Gains for trained scripts maintained for up to 1 year • Untrained scripts and standardized test scores remained relatively stable during follow-up period |
| Henry et al. (2013) | Oral reading | • Decreased speech errors in untrained text and improved self-correction of errors in single participant with mild AOS+PAA • Connected speech remained stable up to 1 year post-treatment |
| Authors’ clinical practice (anecdotal) | Oral reading | • Anecdotal patient reports of benefit or maintenance of speech when adhering to home program of oral reading (e.g., 3-5 minutes at a time, several times daily), following short period of practice with clinician to set targets |
| Beber et al. (2018) | Rate and rhythm strategies | • Qualitatively increased production of single words and short sentences, in uncontrolled study of one patient with AOS+PPA who had difficulty initiating speech primarily because of blocks and sound repetitions |
| Ballard et al. (2015); Duffy (2020) (overviews) | • Articulatory-kinematic and rate/rhythm approaches • Multiple compensatory strategies |
• Various levels of evidence of effectiveness for patients with nondegenerative AOS and other neurodegenerative motor speech disorders • May be applicable to PAOS, particularly compensatory strategies |
| Related Resources (not specific to PPAOS) | ||
| Topic | Association | Website |
| AOS in general | American Speech-Language Hearing Association | https://www.asha.org/practice-portal/ |
| PPA | National Aphasia Association | https://aphasia.org |
| Atypical Alzheimer’s disease | Alzheimer’s Association | https://www.alz.org/alzheimers-dementia/what-is-dementia/types-of-dementia/frontotemporal-dementia |
| Frontotemporal dementia | Association for Frontotemporal dementia | https://www.theaftd.org/what-is-ftd/primary-progressive-aphasia/ |
| Rare dementias | Rare Dementia Support | https://www.raredementiasupport.org/primary-progressive-aphasia/ppa-early-stages/ |
| Tauopathies | National Organization for Rare Disorders | https://rarediseases.org/ |