Table 2.
Reperfusion therapies and in-hospital workflow times
| Control period | Pandemic | Difference | p value | |
|---|---|---|---|---|
| All centers | N = 1,033 | N = 805 | −22% | |
| Reperfusion treatment, n | 304 | 215 | −29% | 0.580 |
| IVT | 167 | 113 | −32% | |
| IVT + MT | 43 | 33 | −23% | |
| MT alone | 94 | 69 | −27% | |
| Door to needle (IVT), min | 35 [25–51] | 34 [26–50] | −1 min | 0.847 |
| Onset to needle (IVT), min | 118 [85–180] | 138 [91–210] | +20 min | 0.024 |
| Door to groin (MT), min | 80 [54–150] | 93 [60–130] | +13 min | 0.461 |
| Onset to groin (MT), min | 213 [130–409] | 267 [162–663] | +54 min | 0.007 |
| TSCs | N = 110 | N = 70 | −36% | |
| IVT, n | 22 | 10 | −55% | 0.328 |
| Door to needle (IVT), min | 42 [32–58] | 59 [39–74] | +17 min | 0.109 |
| Referred to MT center, n | 38 | 18 | −53% | 0.212 |
| PSCs | N = 303 | N = 213 | −29% | |
| IVT, n | 72 | 42 | −42% | 0.276 |
| Door to needle (IVT), min | 34 [24–54] | 33 [25–49] | −1 min | 0.714 |
| Referred to MT center, n | 40 | 29 | −28% | 0.892 |
| CSCs | N = 620 | N = 522 | −16% | |
| Reperfusion treatment, n | 193 | 150 | −22% | 0.755 |
| IVT | 81 | 63 | −23% | |
| IVT + MT | 35 | 31 | −6% | |
| MT alone | 77 | 56 | −27% | |
| Door to needle (IVT), min | 34 [24–50] | 33 [26–49] | −1 min | 0.876 |
| Door to groin (MT), min | 70 [48–96] | 82 [56–115] | +12 min | 0.056 |
Data are presented as n for categorical variables and as median [interquartile range] for continuous variables. TSCs are IVT-ready centers through telemedicine connection to an on-call neurologist, PSCs are IVT-ready centers with the neurologist on-site and Stroke Unit equipped. CSCs are MT-capable centers. IVT, intravenous thrombolysis; MT, mechanical thrombectomy; min, minutes; CSCs, comprehensive stroke centers; PSCs, primary stroke centers; TSCs, telestroke centers.