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. 2021 May 5:1–14. doi: 10.1159/000516038

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Copyright © 2021 by S. Karger AG, Basel

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

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Fig. 3 — The time kinetics between viral load, symptoms, and host immunoglobulins (IgM, IgG) in COVID-19. The onset of symptoms is usually 5 days after infection. Seroconversion may usually be detectable between 5–7 and 14 days after the onset of symptoms. Viral RNA is inversely correlated with neutralizing antibody titers. Higher titers have been observed in critically ill patients. The humoral response in SARS-CoV-1 is relatively short lived, altogether, suggesting that immunity with SARS-CoV-2 may reduce 1–2 years after primary infection. SARS-CoV-2, Severe acute respiratory syndrome coronavirus-2.