Table 2.
Prevalence of major comorbidities in patients with rheumatoid arthritis, stratified by calendar period of disease diagnosis*
|
2003–2007 (n = 12,190) |
2008–2012 (n = 10,565) |
2013–2016 (n = 6,597) |
|
|---|---|---|---|
| Age, mean ± SD years | 52.48 ± 13.94 | 53.60 ± 14.16 | 54.37 ± 14.22 |
| Sex | |||
| No. (%) male | 2,751 (22.57) | 2,635 (24.94) | 1,805 (27.36) |
| No. (%) female | 9,439 (77.43) | 7,930 (75.06) | 4,792 (72.64) |
| Comorbidity, no. (%) | |||
| Cancer | 412 (3.4) | 401 (3.8) | 256 (3.9) |
| Cirrhosis of the liver | 1,411 (11.6) | 975 (9.2) | 516 (7.8) |
| COPD | 1,910 (15.7) | 1,362 (12.9) | 819 (12.4) |
| Diabetes | 984 (8.1) | 973 (9.2) | 707 (10.7) |
| Cardiovascular disease | 1,906 (15.6) | 1,585 (15.0) | 885 (13.4) |
| Hyperlipidemia | 1,610 (13.2) | 1,902 (18.0) | 1,317 (20.0) |
| Stroke | 506 (4.2) | 431 (4.1) | 253 (3.8) |
*
COPD = chronic obstructive pulmonary disease.