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. 2021 Jun 17;11:627282. doi: 10.3389/fonc.2021.627282

Table 2.

Differences in pain reduction according to parameters investigated.

Parameter Absolute pain reduction P value
Histology 0.007
NSCLC 4 (-3 ~10)
Other 5 (-2 ~10)
Age 0.94
 < 65 5 (-3 ~10)
 ≥ 65 5 (-3 ~10)
Gender 0.21
 Male 5 (-3 ~10)
 Female 5 (-2 ~10)
ECOG Performance Status 0.55
 0 5 (-3 ~10)
 1 6 (-3 ~10)
 2 5 (-2 ~10)
 3 4.5 (0 ~10)
 4 9 (9~9)
Postoperative 0.74
 Yes 4.5 (2 ~10)
 No 5 (-3 ~10)
Extension beyond bone 0.23
 Yes 5 (-1 ~10)
 No 6 (-3 ~10)
Site 0.85
 Spine 5 (-3 ~10)
 Upper extremities 5 (1 ~10)
 Lower extremities/pelvis 5 (-3 ~10)
Ribs/chest wall 5 (0 ~10)
 Other 2 (2 ~2)
Total dose 0.23
 ≥2800 5 (-3 ~10)
 <2800 5 (-2 ~10)
Dose/fx 0.26
 >200 cGy 5 (-3 ~10)
 ≤200 cGy 8 (1 ~10)
Dose/fx 0.17
 >300 cGy 5 (-3 ~10)
 ≤300 cGy 5 (-2 ~10)
Number of fractions 0.06
 1 3 (-3~10)
 >1 5 (-2~10)
% kV imaging 0.07
 <90 5 (-3 ~10)
 ≥90 6 (0 ~10)
GTV contoured (entire cohort) 0.54
 Yes 5 (-2 ~10)
 No 5 (-3 ~10)
GTV contoured (patients with extraosseous disease extension) 0.55
 Yes 5 (-1~10)
 No 5 (0 ~10)
GTV volume (n = 131) 0.96
 ≥55 cm3 5 (-2 ~10)
 <55 cm3 5 (-1 ~10)