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. 2021 Feb 1;16(8):1283–1289. doi: 10.1002/cmdc.202000952

Figure 5.

Figure 5

Compound cytotoxicity, off‐target effect, and potency on the rodent malaria parasite PbFNT of MMV007839 (black), BH297 (magenta), and BH267.meta (dark cyan). Cell viability (ATP quantity and resazurin reduction) and proliferation (automated image analysis, nuclei counts) of A) HEK293 and B) HepG2 cell after 24 h of compound treatment. C) Compound off‐target inhibition of the erythrocyte human monocarboxylate transporter 1 (hMCT1), and D) inhibition of PbFNT. Error bars denote S.E.M. (n=3).