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Site‐selective protein dual modification at a single cysteine site to introduce multifunctional bioconjugation reagents. (a) Mono and dibromomaleimide, dibromopyridazinediones (from top to down)[ 47 , 90 ] (b) 3‐Bbromo‐5‐methylene pyrrolones (3Br‐5MPs) [91] (c) Azabicyclic vinyl sulfone [37] (d) Allyl sulfone [38] (e) Dichloro‐1,2,4,5‐tetrazine [44] (f) Ethynylbenziodoxolones (EBXs). [46]
