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. 2021 Jan 28;100(5):971–978. doi: 10.1111/aogs.14042

TABLE 1.

Characteristics of study groups

Variable

High dose of oxytocin

(n = 497)

Low dose of oxytocin

(n = 511)

P value
Maternal age (years)

29.4 (4.7)

29.0 (26; 32)

29.4 (4.7)

29.0 (26; 32)

.96 a
Gestational age (days)

282.0 (7.4)

283.0 (277; 287)

281.6 (6.9)

282.0 (278; 287)

.24 a

Epidural anesthesia

432 (86.9) 438 (85.7) .58 b
Cervical dilation at defined delayed labor (cm)

6.97 (2.48)

6.00 (5.00; 9.00)

n = 478

6.92 (2.46)

6.00 (5.00; 9.00)

n = 501

.75 a

Duration of labor (min)

From active phase of labor to birth

744 (205)

732 (607; 876)

n = 495

773 (198)

762 (639; 899)

n = 511

.018 a

Maximum dose of oxytocin

(mU/min)

(µg/min)

30.61 (22.89)

26.67 (13.33; 39.83)

0.05(0.04)

0.04 (0.02; 0.07)

19.50 (11.69)

16.67 (10.00; 26.67)

0.03 (0.02)

0.03 (0.02; 0.04)

<.001 a

Total oxytocin dose

(mU)

(µg)

4816 (5505)

3080 (1620; 5960)

7.92 (8.28)

5.20 (2.70; 10.00)

n = 497

3613 (3465)

2540 (1300; 4910)

6.01 (5.75)

4.25 (2.20; 8.23)

n = 510

<.001 a
Total duration of oxytocin infusion (hr)

4.64 (2.98)

3.90 (2.50; 6.30)

5.29 (3.18)

4.70 (2.90; 7.20)

<.001 a
Mode of delivery .96 b
Spontaneous vaginal birth 364 (73.2%) 373 (73.0%)
Instrumental vaginal birth 74 (14.9%) 79 (15.5%)
Cesarean section 59 (11.9%) 59 (11.5%)
Postpartum hemorrhage >1000 mL 67 (13.5%) 72 (14.1%) .79 c
Anal sphincter injury (grade 3 or 4) d

23 (5.3%)

n = 438

23 (5.1%)

n = 452

1.00 c
Birthweight (g)

3662 (441)

3650 (3340; 3961)

3628 (428)

3605 (3330; 3900)

.24 a
Apgar score 5 min < 4 1 (0.2%) 0 (0.0%) 1.00 c
Apgar score 5 min < 7 4 (0.8%) 9 (1.8%) .26 c
Admission to neonatal intensive care unit (NICU) 39 (7.8%) 37 (7.2%) .72 c

For categorical variables, n (%) is given.

For continuous variables, mean (SD)/median (Q1; Q3)/ n = is given.

a

Mann‐Whitney U test.

b

Chi‐square test.

c

Fisher’s Exact test.

d

Percentage of vaginal deliveries.