TABLE 1.
Variable |
High dose of oxytocin (n = 497) |
Low dose of oxytocin (n = 511) |
P value |
---|---|---|---|
Maternal age (years) |
29.4 (4.7) 29.0 (26; 32) |
29.4 (4.7) 29.0 (26; 32) |
.96 a |
Gestational age (days) |
282.0 (7.4) 283.0 (277; 287) |
281.6 (6.9) 282.0 (278; 287) |
.24 a |
Epidural anesthesia |
432 (86.9) | 438 (85.7) | .58 b |
Cervical dilation at defined delayed labor (cm) |
6.97 (2.48) 6.00 (5.00; 9.00) n = 478 |
6.92 (2.46) 6.00 (5.00; 9.00) n = 501 |
.75 a |
Duration of labor (min) From active phase of labor to birth |
744 (205) 732 (607; 876) n = 495 |
773 (198) 762 (639; 899) n = 511 |
.018 a |
Maximum dose of oxytocin (mU/min) (µg/min) |
30.61 (22.89) 26.67 (13.33; 39.83) 0.05(0.04) 0.04 (0.02; 0.07) |
19.50 (11.69) 16.67 (10.00; 26.67) 0.03 (0.02) 0.03 (0.02; 0.04) |
<.001 a |
Total oxytocin dose (mU) (µg) |
4816 (5505) 3080 (1620; 5960) 7.92 (8.28) 5.20 (2.70; 10.00) n = 497 |
3613 (3465) 2540 (1300; 4910) 6.01 (5.75) 4.25 (2.20; 8.23) n = 510 |
<.001 a |
Total duration of oxytocin infusion (hr) |
4.64 (2.98) 3.90 (2.50; 6.30) |
5.29 (3.18) 4.70 (2.90; 7.20) |
<.001 a |
Mode of delivery | .96 b | ||
Spontaneous vaginal birth | 364 (73.2%) | 373 (73.0%) | |
Instrumental vaginal birth | 74 (14.9%) | 79 (15.5%) | |
Cesarean section | 59 (11.9%) | 59 (11.5%) | |
Postpartum hemorrhage >1000 mL | 67 (13.5%) | 72 (14.1%) | .79 c |
Anal sphincter injury (grade 3 or 4) d |
23 (5.3%) n = 438 |
23 (5.1%) n = 452 |
1.00 c |
Birthweight (g) |
3662 (441) 3650 (3340; 3961) |
3628 (428) 3605 (3330; 3900) |
.24 a |
Apgar score 5 min < 4 | 1 (0.2%) | 0 (0.0%) | 1.00 c |
Apgar score 5 min < 7 | 4 (0.8%) | 9 (1.8%) | .26 c |
Admission to neonatal intensive care unit (NICU) | 39 (7.8%) | 37 (7.2%) | .72 c |
For categorical variables, n (%) is given.
For continuous variables, mean (SD)/median (Q1; Q3)/ n = is given.
Mann‐Whitney U test.
Chi‐square test.
Fisher’s Exact test.
Percentage of vaginal deliveries.