Table 2.
Inter patient comparison: degree of agreement between single centre- and gold standard- clinical target volumes by axillary nodal level (L2, L3 and L4). Mean values are reported
| Contour | Patient | JI | MDC (mm) | VD (%) | DSC | SI | II | TS |
|---|---|---|---|---|---|---|---|---|
| L2 CTV | P1 | 0.44 (0.16) | 8.70 (4.18) | −39.64 (16.46) | 0.61 (0.17) | 0.49 (0.17) | 0.83 (0.19) | 2.3 |
| P2 | 0.40 (0.12) | 9.05 (2.70) | −32.33 (20.18) | 0.60 (0.12) | 0.51 (0.14) | 0.76 (0.12) | 2.2 | |
| P3 | 0.28 (0.13) | 12.22 (5.80) | 38.21 (53.41) | 0.45 (0.18) | 0.54 (0.24) | 0.40 (0.16) | 1.5 | |
| p-value | 0.017 | 0.111 | <0.001 | 0.024 | 0.537 | <0.001 | ||
| OOO | P3 | P3 | P3 | P3 | ||||
| AVE | 0.37 | 9.99 | 36.73 | 0.55 | 0.51 | 0.66 | ||
| L3 CTV | P1 | 0.42 (0.16) | 10.03 (10.43) | −23.23 (44.11) | 0.59 (0.22) | 0.54 (0.21) | 0.69 (0.26) | 1.8 |
| P2 | 0.43 (0.13) | 8.64 (6.09) | −13.33 (41.50) | 0.64 (0.14) | 0.60 (0.17) | 0.74 (0.16) | 3.0 | |
| P3 | 0.35 (0.19) | 11.80 (12.08) | 44.03 (95.12) | 0.51 (0.25) | 0.57 (0.26) | 0.51 (0.29) | 1.2 | |
| p-value | 0.296 | 0.676 | 0.012 | 0.230 | 0.681 | 0.021 | ||
| OOO | P3 | P3 | ||||||
| AVE | 0.40 | 10.16 | 26.86 | 0.58 | 0.57 | 0.65 | ||
| L4 CTV | P1 | 0.52 (0.12) | 7.39 (1.97) | −25.63 (15.63) | 0.70 (0.10) | 0.61 (0.13) | 0.83 (0.10) | 2.3 |
| P2 | 0.49 (0.08) | 7.78 (1.76) | −32.66 (15.40) | 0.67 (0.07) | 0.57 (0.11) | 0.85 (0.07) | 1.5 | |
| P3 | 0.53 (0.13) | 8.28 (4.23) | −18.04 (22.90) | 0.70 (0.12) | 0.63 (0.13) | 0.80 (0.16) | 2.2 | |
| p-value | 0.429 | 0.625 | 0.192 | 0.471 | 0.681 | 0.886 | ||
| OOO | ||||||||
| AVE | 0.51 | 7.82 | 25.44 | 0.69 | 0.60 | 0.83 | ||
|
Whole CTV (L2 +L3+L4) |
P1 | 0.48 (0.10) | 7.79 (1.91) | −29.25 (13.44) | 0.68 (0.08) | 0.58 (0.09) | 0.83 (0.09) | 2.2 |
| P2 | 0.48 (0.07) | 8.28 (1.67) | −27.83 (14.21) | 0.67 (0.06) | 0.58 (0.09) | 0.81 (0.06) | 2.2 | |
| P3 | 0.39 (0.11) | 9.77 (2.90) | 12.53 (32.13) | 0.60 (0.12) | 0.63 (0.14) | 0.59 (0.15) | 1.7 | |
| p-value | 0.033 | 0.119 | <0.001 | 0.112 | 0.225 | <0.001 | ||
| OOO | P3 | P3 | P3 | |||||
| AVE | 0.45 | 8.61 | 23.20 | 0.65 | 0.60 | 0.74 |
AVE, average; CTV, clinical target volume; DSC, DICE similarity coefficient; II, inclusion index; JI, Jaccard index; L2,L3, L4, lymph node level 2, 3 and 4; MDC, mean distance to conformity; OOO, odd-one-out (the one differing from the others in the group); SI, sensitivity index; TS, total score; VD, volume difference.
Standard deviations (SDs) are put in parentheses. Statistically significant p-values (<0.05) are highlighted in bold.