Table 3.

Inter nodal level comparison: degree of agreement between single centre- and gold standard- clinical target volumes by patient (P1, P2 and P3). Mean values are reported

Patient	Contour	JI	MDC (mm)	VD (%)	DSC	SI	II	TS
P1	L2	0.44 (0.16)	8.70 (4.18)	−39.64 (16.46)	0.61 (0.17)	0.49 (0.17)	0.83 (0.19)	1.8
	L3	0.42 (0.16)	10.03 (10.43)	−23.23 (44.11)	0.59 (0.22)	0.54 (0.21)	0.69 (0.26)	1.5
	L4	0.52 (0.12)	7.39 (1.97)	−25.63 (15.63)	0.70 (0.10)	0.61 (0.13)	0.83 (0.10)	2.8
	p-value	0.164	0.500	0.087	0.194	0.268	0.076
	OOO
	AVE	0.457	8.706	−29.499	0.632	0.548	0.785
P2	L2	0.40 (0.12)	9.05 (2.70)	−32.33 (20.18)	0.60 (0.12)	0.51 (0.14)	0.76 (0.12)	1.3
	L3	0.43 (0.13)	8.64 (6.09)	−13.33 (41.50)	0.64 (0.14)	0.60 (0.17)	0.74 (0.16)	2.2
	L4	0.49 (0.08)	7.78 (1.76)	−32.66 (15.40)	0.67 (0.07)	0.57 (0.11)	0.85 (0.07)	2.5
	p-value	0.125	0.135	0.231	0.209	0.200	0.014
	OOO						L4
	AVE	0.439	8.493	−26.107	0.635	0.557	0.782
P3	L2	0.28 (0.13)	12.22 (5.80)	38.21 (53.41)	0.45 (0.18)	0.54 (0.24)	0.40 (0.16)	1.2
	L3	0.35 (0.19)	11.80 (12.08)	44.03 (95.12)	0.51 (0.25)	0.57 (0.26)	0.51 (0.29)	1.8
	L4	0.53 (0.13)	8.28 (4.23)	−18.04 (22.90)	0.70 (0.12)	0.63 (0.13)	0.80 (0.16)	3.0
	p-value	<0.001	0.042	0.001	0.001	0.796	<0.001
	OOO	L4	L2a	L4	L4		L4
	AVE	0.383	10.768	21.402	0.550	0.580	0.570

AVE, average; DSC, DICE similarity coefficient; II, inclusion index; JI, Jaccard index; MDC, mean distance to conformity; OOO, odd-one-out (the one differing from the others in the group); P1, P2, P3, patient 1, 2 and 3; SI, sensitivity index; TS, total score; VD, volume difference.

Standard deviations (SDs) are put in parentheses.

Statistically significant p-values (<0.05) are highlighted in bold.

^ap-values 0.07 and 0.01 towards L3 and L4, respectively.