Table 3.
Diagnostic value for malignant versus nonmalignant mucinous cystic lesions of needle-based confocal laser endomicroscopy, EUS-FNA and needle-based confocal laser endomicroscopy + EUS-FNA in 35 conclusive patients (per protocol analysis)
| EUS-FNA | nCLEa | nCLE+FNA | |
|---|---|---|---|
| TP (n) | 3 | 6 | 6 |
| FP (n) | 0 | 0 | 0 |
| TN (n) | 27 | 27 | 27 |
| FN (n) | 5 | 2 | 2 |
| Accuracy | 84 (67-95) | 94 (80-99) | 94 (80-99) |
| Sensitivity | 38 (9-76) | 75 (36-96) | 75 (36-96) |
| Specificity | 100 (86-100) | 100 (84-100) | 100 (84-100) |
| PPV | 100 (100-100) | 100 (52-100) | 100 (52-100) |
| NPV | 83 (74-89) | 93 (76-99) | 93 (76-99) |
| LR+ | Infinity | Infinity | Infinity |
| LR- | 62 (37-100) | 25 (8-83) | 25 (8-83) |
aDark aggregates of cells, Data are shown in percentage (95% CI) unless otherwise indicated. nCLE: Needle-based confocal laser endomicroscopy; PPV: Positive predictive value; NPV: Negative predictive value; CI: Confidence interval.