Table 4.
Regression models (unadjusted and adjusted) for risk factors for neurocognitive impairment (N = 144).
| Global neurocognitive impairment** | ||
|---|---|---|
| Yes, n = 41 (28.5%) | ||
| Variable | Unadjusted Prevalence Ratio (95% CI) | Adjusted Prevalence Ratio (95% CI) |
| ≥Age 50 years | 1.27 (0.74–2.19) | – |
| Female sex | 1.14 (0.58–2.24) | – |
| Educational level, secondary school or less | 1.21 (0.72–2.03) | – |
| Hypertension | 0.88 (0.40–1.95) | – |
| Hyperlipidemia | 0.85 (0.48–1.52) | – |
| Anemia | 1.24 (0.59–2.64) | – |
| Depression (self-report) | 1.62 (0.91–2.89) | – |
| Depression (PHQ-9 ≥ 5) | 1.54 (0.92–2.59) | – |
| Anxiety (self-report) | 0.91 (0.38–2.20) | – |
| Current absolute CD4 count<500 (cells/mm3) | 1.64 (0.96–2.8)* | 1.64 (0.87–3.10) |
| Nadir CD4 51–200 (cells/mm3) | 1.13 (0.64–1.99) | – |
| Nadir CD4 <50 (cells/mm3) | 1.68 (0.91–3.09) | – |
| Plasma VL detectable | 0.94 (0.42–2.09) | – |
| HIV duration ≥ 5 years | 1.17 (0.65–2.08) | – |
| Past hepatitis B infection | 1.03 (0.52–2.05) | – |
| Past TB infection | 1.67 (0.93–3.00) | – |
| Past syphilis infection | 0.99 (0.56–1.74) | – |
| Any latent HIV coinfection (hepatitis B, TB, syphilis) | 1.72 (1.04–2.86)¥ | 1.55 (0.81–2.92) |
*
p < 0.10;
¥
p < 0.05;
**
GDS ≥ 0.5.