TABLE 1.
Sample characteristics.
| Groups according to diagnostic outcome |
p-value of Bonferroni’s multiple comparison |
|||||||
| High-risk toddlers (n = 20) | HR-TD (n = 8) | HR-nonTD (n = 3) | HR-ASD (n = 9) | p-value | HR-TD / HR-ASD | HR-TD/HR-non-TD | HR-non-TD/HR-ASD | |
| Mean MRI age [months] (n = 20) | 16.5 ± 1.6 (14.6-19.8) | 17.7 ± 1.5 (15.6-19.8) | 15.3 ± 0.5 (14.8-15.7) | 15.8 ± 1.2 (14.6-18.3) | 0.001 | 0.020 | 0.041 | |
| Time interval between scans [months] (n = 20) | 6.5 ± 0.9 (5.2-9.0) | 6.8 ± 1.4 (5.2-9.0) | 6.1 ± 0.5 (5.6-6.6) | 6.3 ± 0.5 (5.6-7.2) | 0.474 | |||
| Gender (female number) (n = 20) | 5 | 3 | 1 | 1 | 0.427 | |||
| Age at 1nd clinical assesment (n = 19) | 18.1 ± 0.4 (17.6-19.1) | 18.1 ± 0.4 (17.7-18.6) | 17.8 ± 0.2 (17.6-18) | 18.2 ± 0.4 (17.7-19.1) | 0.253 | |||
| ADOS CSS (n = 19) | 3.5 ± 2.7 (1-10) | 2.6 ± 2.1 (1-7) | 2 ± 1 (1-3) | 4.8 ± 3.1 (1-10) | 0.161 | |||
| DQ (n = 19) | 87.1 ± 14.2 (54.1-119.4) | 96.4 ± 14.9 (87.3-119.4) | 85.8 ± 11.8 (72.6-95.5) | 80.4 ± 11.2 (54.1-90.9) | 0.073 | |||
| Age at 3rd clinical assesment (n = 20) | 36.5 ± 1.2 (34.9-39.9) | 36.9 ± 1.4 (35.6-39.9) | 35.7 ± 0.7 (35.3-36.6) | 36.9 ± 1.4 (34.9-38.3) | 0.356 | |||
| ADOS CSS (n = 20) | 3.9 ± 2.6 (1-8) | 1.5 ± 0.5 (1-2) | 2.7 ± 1.5 (1-4) | 6.3 ± 1.3 (5-9) | <0.001 | <0.001 | <0.001 | |
| DQ (n = 20) | 87.5 ± 19.1 (70.8-108.0) | 103.2 ± 5.3 (93.3-109.9) | 76 ± 0.2 (75.9-76.3) | 77.4 ± 20.8 (32.5-103.2) | 0.004 | 0.006 | 0.042 | |
Sample demographics and behavioral information. P-value of statistical comparisons between groups (One-way ANOVA) displayed as well as post hoc comparison between groups (Student’s t-test) with Bonferroni correction for multiple comparison when P-value was < 0.05. Significant differences between groups are highlighted in bold.