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. 2021 Jun 17;12:668324. doi: 10.3389/fgene.2021.668324

Table 3B.

Peak hour and AUC comparison of miRNAs and conventional biomarkers.

AUC/Sensitivity/Specificity
miRNAs Combination miRNAs cTnI hs-cTnT cTnT CK-MB
0.74*; 0.81/76%/88%** 0.81*#; 0.89/78%/92%*## 0.77*; 0.68/48%/98%** 0.73*
0.65*; 0.76/51%/94%**
0.7*; 0.78/58%/96%**
0.86/80%/80.28% 0.90 0.82
0.949, 0.947, 0.791*** 0.989, 1.000, 0.995# 1.000, 1.000, 1.000***
0.881, 0.883, 0.838***
0.798, 0.801, 0.908***
0.855 0.902

The samples were obtained from or after T0. T08, the samples were obtained at 2.2 ± 0.97 h after the onset of chest pain on admission; T09, the time of chest pain; T010, the samples were obtained at 12.4 ± 1.5 h after the onset of AMI symptoms; T011, the time of onset of AMI; Inline graphic, lowest time; Inline graphic, sustain increase;

*

the AUC of miRNAs or classical biomarkers in patients with AMI (including all time points);

**

the AUC of miRNAs or classical biomarkers in patients with chest pain for <3 h;

*#

the AUC of combined miRNAs in patients with AMI (including all time points);

*##

the AUC of combined miRNAs in patients with chest pain for <3 h;

***

the AUC of miRNAs or classical biomarkers at T0 and 4 and 24 h;

#

the AUC of combination of miRNAs at T0 and 4 and 24 h.