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. 2021 Jun 21;15(6):e0009505. doi: 10.1371/journal.pntd.0009505

Table 2. Average costs (mean with 95%CI) per JE case (in US$) according to different classification.

Type No. of cases Direct cost
Medical
Direct cost
Non-medical
Direct cost
Total
Indirect cost Total cost
Prognosis of illness
Non-fatal cases
without sequela
32 2531.24
(1980.32, 3132.03)a
321.09
(248, 388.98)a
2852.33 (2287.71, 3461.67)a 1025.91 (788.14, 1306.05)a 3878.24 (3197.58, 4607.76)a
Non-fatal cases
with mild sequela
18 34868.50 (11564.10, 68231.65)b 1689.10 (572.42, 3304.40)b 36557.59 (12135.79, 70892.16)b 8362.26 (4462.58, 13700.60)b 44919.85 (16796.26, 84114.41)b
Non-fatal cases
with severe sequela
5 42821.85 (23847.72, 59479.06)b 2786.77 (1436.07, 3991.49)b 45608.61 (25864.44, 62876.04)b 35857.44 (27889.12, 39841.60)b 81466.05 (64555.20, 98376.90)b
Fatal cases 5 26346.69 (6539.29, 49283.26)b 1472.84 (409.57, 2895.17) 27819.53 (6948.87, 51201.42)b 26638.04 (23315.28, 30191.88)b 54457.57 (30455.38, 81377.37)b
P-value < 0.001 0.001 < 0.001 < 0.001 < 0.001
Migration
Local 30 27861.77 (12236.78, 46965.10) 1630.62 (819.61, 2625.28) 29492.40 (13167.68, 49287.41) 10580.57 (5757.29, 15544.19) 40072.97 (19784.09, 63219.46)
Migrate 30 7287.40 (3928.74, 11817.09) 435.27 (319.59, 572.39) 7722.67 (4303.81, 12362.63) 5947.01 (2673.82, 9730.57) 13669.68 (7421.61, 21246.06)
P-value 0.079 0.101 0.101 0.141 0.076
Residential location
Urban 17 32756.85 (7483.36, 67595.09) 1558.83 (385.43, 3216.62) 34315.68 (7832.51, 70519.47) 11800.10 (5398.66, 18572.56) 46115.78 (15396.74, 87325.62)
Rural 43 11572.30 (7024.09, 16788.02) 825.03 (517, 1182.28) 12397.33 (7596.82, 17835.28) 6865.71 (3711.77, 10514.81) 19263.05 (11467.06, 27871.23)
P-value 0.389 0.854 0.496 0.337 0.321
Gender
Male 38 20561.31 (8125.31, 36697.75) 1111.14 (525.34, 1857.58) 21672.45 (8695.19, 38599.31) 8345.74 (4578.42, 12226.75) 30018.19 (13925.52, 48877.47)
Female 22 12415.70 (5759.85, 20176.86) 897.88 (396.70, 1472.36) 13313.58 (6225.15, 21718.31) 8122.24 (3272.51, 13609.33) 21435.82 (9795.44, 34374.90)
P-value 0.701 0.821 0.830 0.830 0.927
Age group (years)
0–6 14 4995.50 (2781.93, 7696.60)a 335.66 (151.33, 553.94)a 5331.16 (3017.28, 8149.33)a 1932.31 (1201.08, 2811.23)a 7263.47 (4564.83, 10697.35)a
7–18 20 19145.38 (3522.97, 46073.51)a 715.46 (279.5, 1419.80)a 19860.84 (3837.57, 47444.29) 4077.77 (1042.20, 8075.28)a 23938.61 (4950.97, 55636.85)a
19- 26 23139.64 (12392.34, 36074.20)a 1652.62 (852.52, 2682.49)b 24792.26 (13471.18, 38660.12)b 14893.07 (9174.46, 20496.20)b 39685.33 (23503.39, 57006.44)b
P-value 0.049 0.003 0.026 0.002 0.005
Occupation
Students 30 14147.72 (3584.20, 32164.54) 583.73 (257.31, 1060.88)a 14731.45 (3897.36, 33249.59)a 2984.12 (1095.70, 5766.14)a 17715.57 (5115.04, 39087.68)a
Worker/Farmer 17 12997.54 (6372.75, 20930.80) 847.51 (515.29, 1290.89) 13845.05 (6959.92, 21929.96) 12817.26 (6599.99, 19882.37) 26662.31 (15244.43, 40744.94)
Commercial 7 21021.04 (3692.29, 40334.27) 1545.42 (361.10, 2750.35) 22566.45 (4052.08, 43114.93) 13159.09 (4075.36, 23984.19) 35725.55 (8678.08, 66885.80)
Othersc 6 43656.36 (12816.57, 88971.57) 3206.55 (536.09, 7157.91)b 46862.91 (13916.28, 96180.39)b 16049.46 (4362.63, 28194.35)b 62912.38 (18674.84, 123419.75)b
P-value 0.062 0.009 0.043 0.002 0.012
Vaccination
Yes 16 8349.77 (2729.79, 16943.12) 602.66 (220.34, 1129.28) 8952.43 (2993.61, 18135.83) 4091.22 (1093.53, 8981.40) 13043.66 (4314.25, 26995.56)
No 34 25844.56 (12455.71, 43632.11) 1430.63 (722.95, 2269.59) 27275.19 (13170.62, 45814.15) 12132.91 (7662.27, 17155.56) 39408.09 (22163.85, 61158.53)
Unknown 10 4216.40 (1830.22, 8278.32) 369.27 (290.36, 450.44) 4585.67 (2191.41, 8654.57) 1784.89 (625.61, 3744.89) 6370.56 (3085.26, 12259.73)
P-value* 0.019 0.082 0.015 0.029 0.011
Insurance
Yes 27 31881.54 (15116.59, 54507.68) 1749.43 (833.70, 2892.75) 33630.97 (16097.05, 56931.31) 11669.12 (6327.54, 17206.50) 45300.10 (23814.34, 72370.62)
No 15 7499.31 (2762.52, 15390.69) 402.55 (200.79, 681.38) 7901.86 (3034.22, 15970.68) 6932.43 (1877.99, 12764.85) 14834.29 (5122.90, 27007.70)
Unknown 18 4510.23 (2978.16, 6291.80) 483.54 (482.06, 486.50) 4993.77 (3462.5, 6775.33) 4265.25 (1268.74, 8094.41) 9259.02 (5152.58, 14051.57)
P-value* 0.032 0.164 0.032 0.131 0.057
Overall 60 17574.59 (9538.60, 27701.85) 1032.94 (615.43, 1586.96) 18607.53 (10199.97, 29293.33) 8263.79 (5398.60, 11636.93) 26871.32 (16107.34, 39162.00)

Note

a,b Groups with different letters indicated significant difference through pairwise comparisons for polytomous variables, otherwise indicated no significant difference.

c Including civil servant, technical staff, and the retiree. They were combined due to sparse data.

*Statistical tests were only conducted between those "Yes" and "No".