Table 1. Demographic and clinical characteristics of the BTT and the non-BTT groups at the time of transplantation.
| All (n = 77) | BTT (n = 41) | Non-BTT (n = 36) | P-value | |
|---|---|---|---|---|
| Age, years, median (IQR) | 53 (41–61) | 55 (41–62) | 51 (40–60) | 0.358 |
| Male, n (%) | 51 (66.2) | 26 (63.4) | 25 (69.4) | 0.577 |
| BMI, kg/m2, median (IQR) | 22.6 (19.4–24.9) | 23.1 (20.2–25.4) | 21.6 (16.7–24.4) | 0.109 |
| Blood type, n (%) | 0.655 | |||
| A | 27 (35.1) | 17 (41.5) | 10 (27.8) | |
| B | 23 (29.9) | 11 (26.8) | 12 (33.3) | |
| O | 14 (18.2) | 7 (17.1) | 7 (19.4) | |
| AB | 13 (16.9) | 6 (14.6) | 7 (19.4) | |
| Diagnosis, n (%) | 0.479 | |||
| Interstitial lung disease | 52 (67.5) | 30 (73.2) | 22 (61.1) | |
| Bronchiolitis obliterans syndromea | 7 (9.1) | 2 (4.9) | 5 (13.9) | |
| Pulmonary vascular disease | 5 (6.5) | 3 (7.3) | 2 (5.6) | |
| Others | 13 (16.9) | 6 (14.6) | 7 (19.4) | |
| SAPS II, median (IQR) | 31 (12–39) | 35 (31–49) | 12 (7–19) | <0.001 |
| Type of transplantation | 0.742 | |||
| Double-lung | 67 (87.0) | 35 (85.4) | 32 (88.9) | |
| Heart-lung | 10 (13.0) | 6 (14.6) | 4 (11.1) | |
| Mechanical ventilation, n (%) | <0.001 | |||
| Not required | 27 (35.1) | 1 (2.4) | 26 (72.2) | |
| Intubated | 13 (16.9) | 10 (24.4) | 3 (8.3) | |
| Tracheostomized | 37 (48.1) | 30 (73.2) | 7 (19.4) | |
| Mobilization, n (%) | 60 (77.9) | 31 (75.6) | 29 (80.6) | 0.602 |
| Time to lung transplantation, days, median (IQR) | ||||
| From hospital admission | 16 (1–39) | 29 (14–42) | 1 (0–25) | <0.001 |
| From ICU admission | 10 (0–25) | 16 (10–30) | 0 (0–2) | <0.001 |
| Ischemic time, h, median (IQR) | 4.1 (3.8–4.5) | 4.1 (3.9–4.6) | 4.0 (3.7–4.5) | 0.231 |
| Primary graft dysfunction at 72 hours, n (%) | 0.124 | |||
| Grade 0 or 1 | 26 (33.8) | 11 (26.8) | 15 (41.7) | |
| Grade 2 | 38 (49.4) | 20 (48.8) | 18 (50.0) | |
| Grade 3 | 13 (16.9) | 10 (24.4) | 3 (8.3) | |
| AKI requiring dialysis, n (%) | 18 (23.4) | 11 (26.8) | 7 (19.4) | 0.445 |
| Hypotension requiring vasopressors for > 24 hours, n (%) | 17 (22.1) | 12 (29.3) | 5 (13.9) | 0.105 |
AKI, acute kidney injury; BMI, body mass index; BTT, bridge to lung transplantation; IQR, interquartile range; SAPS II, simplified acute physiologic score II.
aSecondary to the previously treated hematologic malignancies.