Figure 1 .

Timeline of rmTBI experiments and cohorts. Mice were exposed to five weight drop injuries over 5 days. Mice designated to microdialysis or EEG groups were implanted with hardware after the final injury. One week after the final injury animals were assigned to one of the following groups: microdialysis, EEG, 1-week HPLC for oxidative stress (GSH:GSSG), 1-week IHC, 1-week PTZ challenge, 6-week HPLC, 6-week IHC, and 6-week PTZ. Microdialysis measures were obtained weekly for 6 weeks. EEG was recorded once after final verum or sham injury and again 6 weeks after the last verum or sham injury.