Table 2.
Significant nodes of rsFC differences for NAcc, ventral caudate, and dorsal caudate seeds between individuals with BED (n = 27) and WMCs (n = 21)a
| Anatomical location (Brodmann area) | MNI Coordinates (mm) | Cluster (voxels) | t | p | |||
|---|---|---|---|---|---|---|---|
| x | y | z | |||||
| NAcc seed | |||||||
| Frontal | L SFG (BA 9) | −6 | 52 | 43 | 963 | 6.09 | <0.001 |
| Posterior | L posterior cingulate (BA 23) | −2 | −54 | 18 | 269 | 3.88 | <0.001 |
| Ventral caudate seed | |||||||
| Frontal | L SFG (BA 9, 8) | −10 | 52 | 35 | 155 | 5.52 | <0.001 |
| 22 | 32 | 53 | 140 | ||||
| Dorsal caudate seed | |||||||
| Frontal | L SFG (BA 8, 6) | −10 | 50 | 44 | 302 | 5.48 | <0.001 |
| −26 | −6 | 68 | 288 | ||||
| L IFG (BA 47) | −18 | 30 | 52 | 234 | |||
| −50 | 36 | −6 | 103 | ||||
| Parietal | L inferior parietal lobule (BA 40) | −54 | −40 | 22 | 121 | 3.75 | <0.001 |
| Temporal | L middle temporal gyrus (BA 22) | −60 | −38 | 0 | 106 | 4.28 | <0.001 |
| R superior temporal gyrus (BA 41) | 48 | −40 | 20 | 100 | |||
Note: BA, Brodmann area; L, left; R, right.
a z-scores that survived thresholding and clustering (p < 0.01, corrected for multiple comparisons). In all results, WMCs > BED.