Fig. 2.

Treatment strategy and course of disease after initial resection (n = 124) or radiologic diagnosis (n = 4). Multiple treatment lines consisted of one or more courses of chemotherapy and/or radiotherapy ± surgical treatment. ^#Death of aspiration due to central respiratory dysregulation 1.7 years after initial total resection of cervicothoracic dysembryoplastic neuroepithelial tumor WHO-grade I. *Figures before the slash indicate numbers of patients initially observed, figures after the slash refer to numbers of patients who received initial nonsurgical treatment. Abbreviations: CR, complete remission; DMT, death of HGG after MT; DOD, death of disease; MT, malignant transformation with subsequent HGG treatment; PD, recent progressive disease; SD, stable disease; SMN, second malignant neoplasm.