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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Nat Aging. 2021 Jan 14;1(1):29–35. doi: 10.1038/s43587-020-00015-1

Figure 3. Digital aging.

Figure 3.

Cells from the same organ, born at the same time, show distinct temporal patterns of functional decline. These functional changes can be viewed as occurring in digital steps corresponding to discreet states of dysfunction (blue, yellow), resulting in different homeostatic organ states over time. Cells do not necessarily have to follow the same sequences of digital steps and acquire the same levels of dysfunction before they die, shown here as the adoption of brown, apoptotic features.