Appendix 4—table 2. The results of Fisher exact test in different weightings were summarized.
p Values of different OATP weightings were calculated and summarized in this table. p<0.05 indicated significant correlation found between recycle ratios and cell uptake. Results marked in red were eliminated.
| Weighting | p | Weighting | p | |||
|---|---|---|---|---|---|---|
| OATP1B1 | OATP1B3 OATP2B1 | value | OATP1B1 | OATP1B3 OATP2B1 | value | |
| 2 | 3 5 | 0.0079 | 7 | 1 2 | 0.0476 | |
| 2 | 2 6 | 0.0079 | 7 | 0 3 | 0.0476 | |
| 2 | 1 7 | 0.0079 | 8 | 2 0 | 0.0476 | |
| 2 | 0 8 | 0.0079 | 8 | 0 2 | 0.0476 | |
| 3 | 2 5 | 0.0079 | 8 | 1 1 | 0.0476 | |
| 3 | 1 6 | 0.0079 | 9 | 1 0 | 0.0476 | |
| 3 | 0 7 | 0.0079 | 9 | 0 1 | 0.0476 | |
| 4 | 1 5 | 0.0079 | 10 | 0 0 | 0.0476 | |
| 4 | 0 6 | 0.0079 | 0 | 10 0 | 0.1667 | |
| 5 | 1 4 | 0.0079 | 0 | 9 1 | 0.1667 | |
| 5 | 0 5 | 0.0079 | 0 | 8 2 | 0.1667 | |
| 6 | 0 4 | 0.0079 | 0 | 7 3 | 0.1667 | |
| 0 | 3 7 | 0.0476 | 0 | 6 4 | 0.1667 | |
| 0 | 2 8 | 0.0476 | 0 | 5 5 | 0.1667 | |
| 0 | 1 9 | 0.0476 | 0 | 4 6 | 0.1667 | |
| 0 | 0 10 | 0.0476 | 1 | 9 0 | 0.1667 | |
| 1 | 3 6 | 0.0476 | 1 | 8 1 | 0.1667 | |
| 1 | 2 7 | 0.0476 | 1 | 7 2 | 0.1667 | |
| 1 | 1 8 | 0.0476 | 1 | 6 3 | 0.1667 | |
| 1 | 0 9 | 0.0476 | 1 | 5 4 | 0.1667 | |
| 3 | 3 4 | 0.0476 | 1 | 4 5 | 0.1667 | |
| 4 | 4 2 | 0.0476 | 2 | 8 0 | 0.1667 | |
| 4 | 3 3 | 0.0476 | 2 | 7 1 | 0.1667 | |
| 4 | 2 4 | 0.0476 | 2 | 6 2 | 0.1667 | |
| 5 | 4 1 | 0.0476 | 2 | 5 3 | 0.1667 | |
| 5 | 3 2 | 0.0476 | 2 | 4 4 | 0.1667 | |
| 5 | 2 3 | 0.0476 | 3 | 7 0 | 0.1667 | |
| 6 | 4 0 | 0.0476 | 3 | 6 1 | 0.1667 | |
| 6 | 3 1 | 0.0476 | 3 | 5 2 | 0.1667 | |
| 6 | 2 2 | 0.0476 | 3 | 4 3 | 0.1667 | |
| 6 | 1 3 | 0.0476 | 4 | 6 0 | 0.1667 | |
| 7 | 3 0 | 0.0476 | 4 | 5 1 | 0.1667 | |
| 7 | 2 1 | 0.0476 | 5 | 5 0 | 0.1667 |