Appendix 1—key resources table.
| Reagent type (species) or resource | Designation | Source or reference | Identifiers | Additional information |
|---|---|---|---|---|
| Chemical compound, drug | Apigenin-7-O-glucuronide (Api-7-G) | HWI Analytik GmbH | Lot#: 0449059 | |
| Chemical compound, drug | Wogonoside (Won-7-G) | Meilun bio | MB6662 | |
| Chemical compound, drug | Quercetin (Que-3-G) | Sigma-Aldrich | 00310590 | |
| Chemical compound, drug | Scutellarin (Scu-7-G) | Meilunebio | MB7004-S | |
| Chemical compound, drug | Luteolin-3’-glucuronide (Lue-3’-G) | Chengdu Alfa Biotechnology Co.,Ltd. | AF8025306 | |
| Chemical compound, drug | Luteolin-7-glucuronide (Lue-7-G) | Chengdu Alfa Biotechnology Co.,Ltd. | Af7022398 | |
| Chemical compound, drug | Wogonin (Won) | Meilunebio | MB6663 | |
| Chemical compound, drug | Luteolin (Lue) | Meilunebio | MB6799 | |
| Chemical compound, drug | Icaritin (Ica) | Meilunebio | MB7035 | |
| Chemical compound, drug | Icaritin-3-glucuronide (Ica-3-G) | This compound was synthesized by our cooperative lab. | ||
| Chemical compound, drug | Icaritin-7-glucuronide (Ica-7-G) | This compound was synthesized by our cooperative lab. | ||
| Chemical compound, drug | Estradiol-17β-glucuronide (E2G) | Steraloids Company | E1073-000 | |
| Chemical compound, drug | Estrone-3-sulfate (E1S) | Steraloids Company | E2335-000 | |
| Chemical compound, drug | Raloxifene (Ral) | Toronto Research Chemical | R099995 | |
| Chemical compound, drug | Raloxifene-4’-glucuronide (Ral-4’-G) | Toronto Research Chemical | R100020 | |
| Chemical compound, drug | Raloxifene-6-glucuronide (Ral-6-G) | Toronto Research Chemical | R100025 | |
| Chemical compound, drug | Ezetimibe (Eze) | Toronto Research Chemical | E975000 | |
| Chemical compound, drug | Ezetimibe-4’-phenoxy-glucuronide (Eze-4’-G) | Toronto Research Chemical | E975030 | |
| Chemical compound, drug | Apigenin (Api) | Indofine | A-002 | |
| Chemical compound, drug | Baicalein (Bai) | Indofine | B-101 | |
| Chemical compound, drug | Baicalein-7-glucuronide (Bai-7-G) | Indofine | 06–012 | |
| Chemical compound, drug | Dimethyl sulfoxide (DMSO) | Sigma-Aldrich | 276855 | |
| Chemical compound, drug | Hanks balanced salt solution (HBSS) | Sigma-Aldrich | H1387 | |
| Chemical compound, drug | Acetonitrile (ACN) | Omni Solv | AX0149 | |
| Chemical compound, drug | methanol (MeOH) | Omni Solv | MX0486 | |
| Chemical compound, drug | ORA-Plus suspending vehicle | Perrigo | 0574-0303-16 | |
| Cell line (Homo-sapiens) | HEK-293 OATP1B1/1B3 over-expressed cell line | Dr.Yue Wei’s Lab | The related publication could be searched by using PMID:29538325 | |
| Cell line (Homo-sapiens) | HEK-293 OATP2B1 over-expressed cell line | Dr. Per Artursson’s Lab | The related publication could be searched by using PMID:24799396 |
|
| Software, algorithm | GraphPad Prism 6 | GraphPad Software Inc | RRID:SCR_002798 |