Table 1.
Body weight and brain weight of WT and FGL2 KO offspring after intrauterine inflammation.
| Group | E16.5 | P1 | P7 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Body weight (g) | Brain weight (g) | Brain/body weight (%) | Body weight (g) | Brain weight (g) | Brain/body weight (%) | Body weight (g) | Brain weight (g) | Brain/body weight (%) | |
| WT/SAL | 0.482 ± 0.054 | 0.044 ± 0.005 | 9.110 ± 0.780 | 1.463 ± 0.090 | 0.095 ± 0.008 | 6.487 ± 0.338 | 5.128 ± 0.240 | 0.263 ± 0.008 | 5.064 ± 0.190 |
| WT/LPS | 0.501 ± 0.064 | 0.045 ± 0.005 | 8.736 ± 0.969 | 1.362 ± 0.084* | 0.092 ± 0.012 | 6.723 ± 0.637 | 4.584 ± 0.391* | 0.254 ± 0.009 | 5.561 ± 0.295* |
| FGL2 KO/SAL | 0.475 ± 0.084 | 0.044 ± 0.008 | 9.316 ± 0.764 | 1.437 ± 0.037 | 0.091 ± 0.002 | 6.359 ± 0.060 | 5.029 ± 0.128 | 0.252 ± 0.009 | 5.012 ± 0.167 |
| FGL2 KO/LPS | 0.487 ± 0.060 | 0.044 ± 0.007 | 9.242 ± 1.662 | 1.473 ± 0.054† | 0.095 ± 0.003 | 6.429 ± 0.172 | 5.071 ± 0.390† | 0.257 ± 0.007 | 5.087 ± 0.347† |
Body weight and brain weight were measured and brain-to-body weight ratio was calculated on E16.5 (n = 12 for each group), P1 (n = 9 for each group), and P7 (n = 9 for each group). Data are expressed as mean ± SD.
*P < 0.05 WT/LPS versus WT/SAL.
†P < 0.05 FGL2 KO/LPS versus WT/LPS.