Fig. 3.

Results of ALK status confirmed using fluorescence in situ hybridization (FISH) or Sanger sequencing. ALK status of a specimen F182120-1A tested using reverse transcription polymerase chain reaction (RT-PCR) and Sanger sequencing; b specimen P01002-1B tested using RT-PCR and FISH (magnification × 60); c specimen 1911802 tested using RT-PCR and FISH (magnification × 60); d specimen 1910754-1 tested using RT-PCR and FISH (magnification × 60); e specimen 1902861 tested using RT-PCR; and f specimen 1910882 tested using FISH (magnification × 60). White arrows indicate split red-green signal indicative of EML4-ALK fusion, red arrows indicate isolated red signals indicative of EML4-ALK fusion. ALK anaplastic lymphoma kinase