Table 4.

Revised NIH-HIES score for predicting the likelihood of a STAT3 dominant-negative mutation in a patient with serum IgE > 1000 IU/ml.

Modified from Woellner et al. [50]

Clinical finding	Points						Scaling factor
	0	2	4	5	6	8
Pneumonia (X-ray proven, total no.)	None	1	2	–	3	> 3	2.5
Newborn rash	Absent	–	Present	–	–	–	2.08
Pathological bone fractures (total no.)	None	–	1–2	–	–	> 2	3.33
Characteristic facies	Absent	Mild	–	Present	–	–	3.33
High-arched palate	Absent	Present	–	–	–	–	2.5