Table 5.

A two-way ANOVA analysis of metabolites taking into account the sample timepoint (Time) and the effect of the group (Factor), i.e., control vs. treatment group.

NNMR data		Time(raw.p)	Time(adj.p)	Factor(raw.p)	Factor(adj.p)	Interaction(raw.p)
3.1405	Dimethylsulfone	0.006449	0.41649	2.39E−07	0.000835	0.30133
3.1415	Dimethylsulfone	0.008492	0.41649	9.72E−07	0.001501	0.39066
3.1395	Dimethylsulfone	0.010088	0.41649	1.29E−06	0.001501	0.42122
3.1425	Dimethylsulfone	0.011623	0.41649	8.11E−06	0.006362	0.54783
3.1435	Dimethylsulfone	0.019075	0.41649	6.61E−05	0.017793	0.69828
3.1385	Dimethylsulfone	0.048665	0.41649	4.58E−05	0.014563	0.54441
2.7765	Unknown	0.05342	0.41649	0.000239	0.049286	0.44754
2.7755	Unknown	0.058283	0.41649	0.000185	0.04324	0.49582
2.4135	Unknown	0.16904	0.41649	0.00022	0.048163	0.37797
2.5945	Methylamine	0.36387	0.52756	1.70E−05	0.008492	0.57962
2.5955	Methylamine	0.39142	0.54966	2.39E−05	0.009409	0.64331
2.5935	Methylamine	0.47239	0.61876	1.09E−05	0.006362	0.64923
2.5965	Methylamine	0.51512	0.65026	3.00E−05	0.010497	0.74757
2.5905	Methylamine	0.64991	0.74924	0.000141	0.035276	0.75996
2.5975	Methylamine	0.72159	0.7947	5.70E−05	0.016639	0.78131
2.5925	Methylamine	0.73149	0.79781	9.65E−06	0.006362	0.8052
2.5915	Methylamine	0.90805	0.92766	2.42E−05	0.009409	0.83179

Note. Metabolites that had a significant factor effect (control/treatment) are listed. No difference was attributed to Group at any timepoint.