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. 2021 Jul 1;11:13646. doi: 10.1038/s41598-021-93059-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Correlation between RISK6 signature scores and mycobacterial loads determined by sputum smear microscopy in ATB patients. Boxplots comparing the RISK6 score levels stratified according to sputum smear grade: Negative smears, low grade positive smears (1+ or scanty) and high grade positive smears (2+ or 3+). Horizontal lines designate medians, boxes represent the inter-quartile ranges (IQR) and the ranges are represented by whiskers. Individual dots represent the results of patients with a RISK6 scores out of IQR. Statistical significance was calculated using Mann–Whitney U test. Ns non-significant, ***indicates a p-value < 0.001. HD Healthy donors.